Medicinal plants extract using processing of herbal medicine and composition of skin external application comprising the same

ABSTRACT

The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for skin external application contains an extract of processed herbal medicinal plant, prepared through a method comprising the steps of: (a) processing an herbal medicinal plant by a process of boiling, steaming, roasting, baking or heating the medicinal plant or a combination of two or more of these processes; (b) obtaining an extract of the processed medicinal plant. The composition shows an improved antioxidant effect.

This application is a divisional of application Ser. No. 12/990,699filed Nov. 2, 2010, which in turn is a U.S. national phase ofInternational Application No. PCT/KR2008/006545 filed 6 Nov. 2008, whichdesignated the U.S. and claims priority to KR Application No.10-2008-0041544 filed 2 May 2008, the entire contents of each of whichare hereby incorporated by reference.

TECHNICAL FIELD

The present invention relates to a medicinal plant extract preparedusing Chinese herbal medicine processing and a cosmetic compositioncontaining the same.

BACKGROUND ART

The processing of medicinal plants is a pharmaceutical technology ofchanging the inherent properties of herbal medicines by processing theherbal medicines based on Chinese medicinal theory. Any herbal medicineis toxic or intense in nature, and thus cannot be directly takeninternally, any herbal medicine has medicinal properties which easilychange, and thus cannot be stored for a long period of time, and anyherbal medicine can be used only after impurities and somes parts areremoved. Even in the case of the same medicinal plant, the unprocessedmaterial and the processed material have different properties ordifferent actions. Such herbal medicines must be processed before use,and this operation is called the “processing” of herbal plants. Theprocessing method is a traditional pharmaceutical technology and hasvarious Korean names, including Hapwha, Hapyak, Suchi, Poja and Susa.

The objects of processing Chinese herbal medicines are to: (1) makemedicine clean and facilitate the storage of medicine; (2) reduce orremove the toxicity or side effects of medicine; (3) change the natureof medicine to make the medicines more effective; (4) enhance thetherapeutic effects of medicine; and (5) remove the offensive odor andtaste of medicine to make it better to take the medicine.

The processing of herbal medicine is performed in various manners, andspecific examples of the processing method are as follows:

(1) Roasting: this is a method of roasting herbal medicine, and theroasting temperature and time and the degree of roasting are important.In the roasting operation, heating power must be maintained at a uniformlevel, and continuous agitation is required for uniform heating.

1) Roasting without adding auxiliary material: this is a method ofroasting herbal medicine with weak fire or strong fire to a prescribeddegree.

(i) Roasting to yellow color: herbal medicine is placed in a vessel androasted with weak fire to a prescribed degree.

(ii) Roasting to brown color: herbal medicine is placed in a vessel androasted with weak fire, until the outer surface of the medicine becomesbrown. The medicine is roasted either until the color of the section isturned dark or to a prescribed degree. Herbal medicine which is easilyburned in the roasting process is wet with a small amount of clear waterand roasted again or dried in sunlight.

(iii) Roasting to black or brown color: herbal medicine is placed in avessel and roasted with weak fire to a prescribed degree, until thesurface is burned black or the inner part is burned yellow. The roastedmaterial is wetted with clear water, and then dried.

2) Roasting together with auxiliary material: this is a method in whicha solid auxiliary material is placed in a vessel and a heated to aprescribed degree, and then herbal medicine is added thereto androasted, and then the auxiliary material is filtered out.

(i) Roasting to yellow color or dark color: wheat bran is placed in apreviously warmed vessel and heated until it smokes. Then, herbalmedicine is placed in the vessel and agitated uniformly, and it isroasted until the color of the outer surface becomes yellow or dark.Then, the wheat bran is discarded, and the roasted material is cooled.Generally, 5-10 kg of wheat bran is used for 100 kg of herbal medicine.

(2) Baking: this is a method of roasting herbal medicine together with aspecific amount of liquid auxiliary material to impregnate the auxiliarymaterial into the tissue of the medicine.

(i) Baking together with alcohol: about 15% alcohol is generally used,and when Soju is used, the concentration of ethanol must be adjustedbefore processing of herbal medicine. Herbal medicine is added toalcohol, roasted in a vessel with weak fire to a prescribed degree, andthen cooled. Generally, 10-15 kg of alcohol is used for 100 kg of herbalmedicine.

(ii) Baking together with vinegar: vinegar is added to and uniformlymixed with herbal medicine, and the mixture roasted in a vessel to aprescribed degree and cooled. Generally, 10-15 kg of vinegar is used for100 kg of herbal medicine.

(iii) Baking together with table salt: table salt is dissolved in asuitable amount of water, and then filtered. Herbal medicine isuniformly mixed or wetted with the salt water, placed in a vessel,roasted to a prescribed degree, and then cooled. Generally, 2 kg oftable salt is used for 100 kg of herbal medicine.

(iv) Baking together with ginger: ginger is pounded, a suitable amountof water is added thereto, and the ginger solution is squeezed underpressure to obtain a juice. The juice is combined with a juice obtainedby adding a suitable amount of water the ginger remnants and boiling thesolution, thus preparing a ginger juice. When dry ginger is used, it ispounded in a mortar and boiled twice to make a juice. The ginger juiceis added to herbal medicine, and the mixture is placed in a vessel androasted with weak fire to a prescribed degree, until the ginger juice iscompletely absorbed into the herbal medicine. The roasted material isdried. Generally, 10 kg of ginger or 3 kg of dry ginger is used for 100kg of herbal medicine.

(v) Baking together with honey: boiled honey is dissolved in a suitableamount of hot water, and then the honeyed water is sprinkled on orimmersed in herbal medicine. The resulting herbal medicine is roastedwith weak fire to a prescribed degree and cooled. Generally, 25-30 kg ofhoney is used for 100 kg of herbal medicine.

(3) Boiling: according to the processing regulation of each herbalmedicine, a liquid auxiliary material is added to herbal medicine, andthe mixture is boiled until the auxiliary liquid is completely absorbedor until the white color of the inner part of the cut herbal medicinedisappears. The boiled material is dried. After toxic herbal medicine isboiled, the remaining juice must generally be discarded.

(4) Heating: according to the processing regulation of each herbalmedicine, a liquid auxiliary material is placed in a suitable closedvessel, and herbal medicine is added thereto and heated in water bath orsteamed with water vapor, until the auxiliary liquid is completelyabsorbed into the herbal medicine. The heated material is dried.

(5) Steaming: according to the processing regulation of each herbalmedicine, a liquid auxiliary material was added or not added to herbalmedicine, and the herbal medicine is steamed by heat in a suitablevessel or steamed to a prescribed degree. The steamed material is dried.

(6) Stirring: auxiliary materials such as clean sand, seashell powderand talc are used. Sand (or seashell powder or talc) is heated in avessel, and herbal medicine is added thereto and stirred. When thestirred material is heated to a prescribed degree, it is taken out ofthe vessel and sieved to remove the sand, followed by cooling.

(7) Calcination: the degree of heating with fire is important, and anoperation must be carried out such that herbal medicine is soft andeasily smashed. Herbal medicine is cleaved into small lumps and heatedin a fire pot which does not smoke or in a suitable vessel. When it isturned red, it is taken out of the vessel and cooled. Alternatively,immediately after it is heated red, it is immersed in a liquid auxiliarymaterial, taken out of the material and dried. Then, the herbal materialis either smashed or powdered with a mortar.

(8) Fermentation

Herbal medicine is fermented using fungi at a given temperature tochange the inherent properties thereof, thus creating new therapeuticeffects. Herbal medicine is naturally fermented in an environment havingsuitable temperature and humidity. In the fermentation process, thetemperature and relative humidity are preferably 30-37° C. and 70-80%,respectively.

(9) Germination

This is a method of sprouting completely ripe fruits or seeds at a giventemperature and humidity. In the method, fruits or seeds are immersed inwater for about 6-12 hours and placed in a vessel which is well drained,and water is sprinkled on the fruits or seeds several times a day.Temperature and humidity are controlled with wet cloth. The temperatureis maintained at 18-25° C., and the water content of the seeds or fruitsis maintained at 40-45%. Alternatively, the humidity is maintained bysprinkling water every day. When the seeds or fruits are germinated andgrow to about 0.6-1 cm, they are taken out and dried.

Although the above-described methods can be used alone, a suitablecombination of the methods (e.g., a nine times steaming and nine timesdrying process) may also be used.

Meanwhile, it is known that reactive oxygen species which are producedby various physical, chemical and environmental factors, includingenzyme systems, reduced metabolites, chemicals, pollutants andphotochemical reactions, act as nonselective irreversible inhibitorsagainst lipids, proteins, sugar and DNA, which are the structuralcomponents of cells, thus causing various diseases, including cell agingand cancer. Also, various peroxides, including lipid peroxides which areproduced as a result of lipid peroxidation by these reactive oxygenspecies, cause oxidative damage to cells, leading to various functionaldisorders, thus causing various diseases.

Accordingly, antioxidants such as free radical scavengers or peroxideproduction inhibitors can be used as agents for inhibiting or treatingaging and various diseases, which are caused by these oxides.

In addition, in order to develop natural antioxidants, many naturallyoccurring materials have been studied. Most naturally occurringmaterials have been used in the form of simple extracts, and it isunclear what compound of the extracts is attributable to the effects ofthe extracts. Also, the extracts are being used in cosmetic products andthe like on the basis of experience and oral tradition.

DISCLOSURE Technical Problem

Accordingly, the present inventors have conducted studies on existingmedicinal plants after processing to solve the above-described problemsand to find more excellent antioxidant materials and, as a result, havefound that extracts of the processed medicinal plants have moreexcellent antioxidant effects, thereby completing the present invention.

It is, therefore, an object of the present invention to prepare amedicinal plant extract through the processing of herbal medicine and toprovide a cosmetic composition which contains the extract as an activeingredient, and thus has an antioxidant effect.

Technical Solution

An extract of a medicinal plant which is used in the present inventionis prepared through Chinese herb processing, and a composition for skinexternal application which contains the extract as an active ingredientcan provide an antioxidant effect.

The medicinal plant that is used in the present invention is at leastone selected from the group consisting of The medicinal plant that isused in the present invention is at least one selected from the groupconsisting of Terminalia chebula Retz flesh, Pueraria root, Angelicakoreana, Chrysanthemum indicum, Rehmanniae radix, Rhus vernicifluaStokes, licorice, dried ginger, Pharbitidis semen, Cassiae semen, Meliaecortex, Angelica tenuissima, Sophora flavescens, Caragana chamlagu,Trichosanthes semen, Lycii fructus, Agastache rugosa, Selaginellainvolvens, Citrus peel, Lonicera japonica flower, Chrysanthemumzawadskii, Chrysanthemum indicum, Platycodon grandiflorum, Cudraniatricuspidata, Raphani semen, Arisaema amurense, Cervi cornus colla,Phaseolus aureus, antler velvet, Trapa japonica fruit, Brassica rapa,Angelica acutiloba, Citrus grandis osbeck, Circium japonicum, Glycinesemen germinatum, Datura stramonium, Zizyphus jujuba, Dae-cheong-chow,Rheum undulatum, Persicae semen, Aralia continentalis Kitagawa,Cordyceps militaris, Eucommiae cortex, Ephedra sinica, Portulacaoleracea, Rhododendron brachycarpum, Codonopsis pilosulae radix, malt,Liriopis tuber, Chaenomeles Sinensis fruit, Akebiae Saussurea lappa,Mui, Moutan cortex radicis, Mentha arvevsis, Bang-pung, Pinelliaternata, Chinese cabbage, Bak-gul-chae, Pulsatilla Koreana root,Cynanchi radix, Bletilla striata tuber, Santalum album, Ampelopsisjaponica root, white Poria cocos, Aconitum koreanum, Thujae orientalissemen, Hedyotis diffusa, Paeonia japonica, Angelica dahurica root,Atractylodes macrocephala rhizome, Rubus coreanus fruit, Poria cocos,Arecae pericarpium, Aconiti radix, Allium tuberosum, Ostericumsieboldii, borneol, Sa-kwa-rak, Adenophorae radix, wild ginseng radix,Crataegus pinnatifida fruit, Cornus officianalis fruit, Dioscorearhizoma, Zizyphi spinosi semen, Gardenia fructus, Saururus chinensis,Atractylodes japonica Koidzumi, Sang-gi-saeng, Mori cortex radicis,Dichroa febrifuga, Morus alba leaf, Abrus precatorius, ginger, Rhizomaacori graminei, Agrimonia pilosa ledebour, Seol-kyun-cho, Asarumsieboldi, Perilla frutescens var. acuta, Pinus densiflora, Jasminumfloridum root, Anethum graveolens, Euphorbia lathyris seed, Dipsacusasper, Tricholoma matsutake, Cimicifuga heracleifolia, Bupleurumfalcatum, Massa medicata fermentata, Artemisia leaf, Yakssuk, Lespedezacuneata, Polygonum multiflorum root, Houttuynia cordata, Forsythiafruit, Nelumbinis semen, Nelumbo nucifera seed, Litchi chinensis,Papaver somniferum flower, Ganoderma lucidum, Aconitum carmichaeli,Acanthopanax sessiliflorus bark, Schizandra chinensis fruit, ChinensisGalla, Evodia officinalis, Linderae radix, Maydis stigmata, Polygonatumodoratum root, Orostachys japonicus, Solani nigri herba, Gentiana scabraBUNGE, Euphoria longana testa, Achyranthes japonica root, Polygalaeradix, Genkwa flos, Oenothera odorata, Clematis mandshurica, Ulmiradicis cortex, Brassica campestris, Cistanche deserticola stem,Gypsophila oldhamiana root, Eumn-yang-qwak, Coicis semen, Ik-mo-cho,Alpinia oxyphylla fruit, ginseng, In-jin, Angelica acutiloba root,Securinega suffruticosa, Cnidium officinale, Aster root, Lithospermumerythrorhizon, Paeonia, Adenophora triphylla, Ailanthus altissima bark,Grifola umbellata, Poria cocos red, Polygonum multiflorum Thunberg, redcabbage, Paeoniae Radix Rubra, Anthriscus sylvestris, Sorbus commixtacortex, Syzygium aromaticum, Gleditsiae fructus, Gleditsiae spina,Lophatherum gracile, Cistanche deserticola, Phyllostachys nigra sheath,Lycium chinensis root, Hovenia dulcis bark, Anemarrhena asphodeloides,Kochiae fructus, Poncirus trifoliate fruit, Sanguisorba officinalis,Rehmannia glutinosa, Aconitum pseudolaeve Nakai, Jin-O-ga-pi,Phyllanthus urinaria, Citrus unshiu peel, Plantaginis semen, Xanthiumstrumarium fruit, Cnidii rhizoma, Gastrodia elata, Asparaguscochinchinensis, Zanthoxyli fructus, Semiaquilegia adoxoides, Opuntiahumifusa, Dioscorea nipponica Makino, Saussurea involucrata,Trichosanthes kirilowii root, Artemisia apiaceae Herba, Amomi tsao-kofructus, Aconiti ciliare tuber, Gardeniae fructus, Celosiae semen,Althaea rosea, Aquillaria agallocha, Taek-ran, Alisma canaliculatum,Ponciri fructus, Smilacis chinae radix, Cuscutae semen, Ligusticumrhizome, Tetrapanacis medulla, Morinda offcinalis How, Tiglii semen,Taraxaci Herba, Typhae pollen, Calypso bulbosa, Polygonum multiflorumtuber, Aeschynomene indica, Armeniacae semen, Helianthus annus seed,Cyperus rotundus, Elsholtzia ciliata, Cedrela sinensis fruit, Typhaorientalis pollen, Scrophulariae radix, Geranium nepalense, Corydalisturtschaminovii, Schizonepeta tenuifolia, Sesamum indicum, Trigonellafoenum-graecum, Cucurbita spp, Acanthopanax giraldii, red ginseng,Kombucha, Herba Trifolii pratensis, Carthamus tinctorius, floralenvelop, Scutellaria baicalensis Georgi, Astragalus membranaceus, Coptischinensis Franch, Polygonatum lasianthum radix, Lindera obtusilobabranch, Phellodendron amurense bark, Magnolia obovata, black Pharbitissemen, and Siegesbeckiae Herba.

Terminalia chebula Retz flesh which is used in the present invention isa flesh obtained by removing seeds from the ripe fruit of Terminaliachebula Retzius and drying the remaining fruit and is used for thetreatment of diarrhea, dysentery, proctocele and the like.

Pueraria root which is used in the present invention refers to the rootof an arrowroot and is used to relieve fever, sweat, relieve thirst andtreat headache, lumbago, neck-shoulder-back pain and the like.

Angelica koreana which is used in the present invention is a biennial orperennial plant belonging to the family Umbelliferae and grows to aheight of more than 2 m. The leaves are divided, alternate andimparipinnate. Small and white flowers blooms at the end of the branchesbetween August and September, and the fruit thereof is oval. The rootsimilar to that of a balloon flower is used as analgesic and antipyreticagents.

Chrysanthemum indicum which is used in the present invention growsmainly in mountains and has short hairs throughout the grass. The stemgrows to a height of 60-90 cm and is black in color and elongates. Theflower is dried in October and added to alcoholic beverage, and theyoung leaves are used to prepare seasoned vegetables. The flower is alsoused for ornamental purposes, because it has a deep fragrance. InChinese medicine, the plant is used for the treatment of fever,pneumonia, bronchitis, headache, gastritis, enteritis, a boil and thelike.

Dried Rehmannia radix which is used in the present invention refers tothe dried root of Rehmannia glutinosa and is used to alleviate fever,supplement blood and stop bleeding.

Rhus verniciflua Stokes which is used in the present invention is oneobtained by collecting the sap of the lacquer tree and drying thecollected sap and is used for menstrual disorders, extravasated blood,ascariasis and the like.

Licorice is a medicinal plant, and the root has a red-brown color andpenetrates deeply into soil. The stem is angular and grows upright to aheight of about 1 m. Because white hairs grow thick, the plant lookslike light gray, and linear dots disperse. The flowers blooms betweenJuly and August, has a length of 1.4-2.5 cm and is purple in color, andthe root has a sweet taste, and thus is used as a sweetening agent or aChinese medicinal material.

Dried ginger which is used in the present invention is used for thetreatment of stomach coldness, vomiting, diarrhea and the like.

Pharbitidis semen which is used in the present invention refers to theseed of a morning glory having a white or black color. The seed has abitter taste and a cold nature and facilitates urination and defecation.It is used for the treatment of constipation, edema, Juk-Chui (abdominalmass), lumbago and the like.

Cassiae semen which is used in the present invention refers to the seedof Cassia obtusifolia which is an annual plant belonging to the familyLeguminosae. The stem of the plant grows a height of about 1 m, andyellow flowers bloom in summer. The fruit of the plant forms a longishcapsule bent like an arrow, and the seed in the capsule is Cassiaesemen.

Meliae cortex which is used in the present invention refers to the rootor bark of Picrasma quassioides. It is used as a vermicide or the like.

Angelica tenuissima which is used in the present invention is aperennial plant belonging to the family Umbelliferae, grows in the deeprecesses of mountains and is distributed in various regions of Korea. Itgrows to a height of 30-80 cm, has no hair throughout thereof and emitsfragrance. The plant bears oval fruits, and the root thereof is used formedicinal purposes. In Chinese medicine, the root gathered in the fallis used after drying to headache, arthralgia, dentalgia, abdominal pain,diarrhea, eczema and the like.

Sophora flavescens which is used in the present invention is a perennialplant belonging to the family Leguminoseae and grows to a height of80-100 cm. In the plant, light-yellow, butterfly-shaped flowers bloom atthe stem and branch end in racemes in summer. It bears narrow fruits,and the root is used for medicinal purposes. The root of Sophoraflavescens is mainly used, and it has a bitter taste and a cold nature,and thus is used for the treatment of jaundice, malaria, dischargingblood and the like.

Caragana chamlagu which is used in the present invention is a deciduousbroad-leaved tree belonging to the family Leguminoseae, grows to aheight of about 2 m and is thorny. The leaves are alternate andimparipinnate, and butterfly-shaped yellowish red flowers individuallyappear at the leaf axil. The fruit of the plant is a cylindrical narrowfruit and is ripe in the fall. The plant is cultivated for ornamentalpurposes and distributed in Korea, China and the like.

Trichosanthes semen which is used in the present invention refers to theseed of a perennial climbing plant belonging to the familyCucurbitaceae. The plant grows to a height of 3-5 m, and the leaves arealternate and divided into a palm shape. Purple flowers blossom at theleaf axil between July and August, and the fruit has a ball shape and isripe and golden. The seed is used to facilitate milk ejection, urinationand defecation or to alleviate swellings.

Lycii fructus which is used in the present invention is the fruit ofLycium chinense and has an oval shape and a length of 1.5-2.5 cm. It isripe and turns red from July and is harvested between July and November.It is used as antipyretic and analeptic agents.

Agastache rugosa which is used in the present invention is a perennialplant belonging to the family Lamiaceae, and the stem is 20-30 cm inheight and is hairy throughout thereof. The leaf thereof is ovate andserrated. Lip-shaped light red flowers bloom in racemes between July andSeptember. The plant grows in mountains and is distributed mainly inJeju, Hamgyeongbuk-do and the like of Korea.

Selaginella involvens which is used in the present invention is aperennial plant belonging to the family Selaginellaceae, and the stemthereof is about 30 cm in height and has many branches. The leaf has adark green color and is scaly. In a dry environment, the branch isrevolute, and in a wet environment, the branch spreads. The plant isused for the treatment of menstrual irregularity, discharging blood andthe like.

The Citrus peel which is used in the present invention refers to thepeel of Citrus unshiu. It has a warm nature, and thus helps digestionand has medicinal effects on coughing, diarrhea, abdominal mass and thelike.

The Lonicera japonica flower which is used in the present inventionrefers to the flower of Lonicera japonica, acts to lower fever andneutralize poison and is used for malignant swelling.

Chrysanthemum zawadskii which is used in the present invention is aperennial plant belonging to the family Compositae and grows to a heightof about 50 cm. Red or white flowers appear at the end of the stalkbetween September and November, produce achenes and are added to alcoholdrinks. The dried stalk and leaf of the plant are used, and in Chinesemedicine and folk remedies, all parts of the plant including the flowerare used for paralysis, women's' diseases, stomach troubles and thelike.

Chrysanthemum indicum which is used in the present invention is aperennial plant belonging to the family Compositae and grows to a heightof about 1 m. It bears flowers mainly in the fall, and the followershave various shapes and colors. It is classified into dae-guk (largeflower), joong-guk (medium flower), and so-guk (small flower).

Platycodon grandiflorum which is used in the present invention is aperennial plant belonging to the family Campanulaceae and grows to aheight of 40-100 cm. The leaves of the plant are alternate and oval inshape. The root is chubby, and the stalks emerge individually or ingroups. White or sky-blue flowers bloom in July or August, and the fruitis a capsule type. The root is eaten or used as antitussives orexpectorants.

Cudrania tricuspidata which is used in the present invention is adeciduous tree belonging to the family Moraceae and is thorny at thebranch, and the shoot is haired. The leaves are alternate and sometimesdivided into 3 leaflets. In May or June, the male flower blooms yellow,and the female flower blooms in the shape of a ball having a diameter ofabout 1 cm. Several fruits are clustered together like a large fruit andare ripe and turn red in September. The plant is known to be effectivein treating tinnitus.

Raphani semen which is used in the present invention refers to the seedof Raphanus sativus Linne or other plants belonging to the familyCruciferae. It is used to cure a digestive upset or phlegm.

Arisaema amurense which is used in the present invention is a perennialplant belonging to the family Araceae and grows to a height of 30-60 cm,and the leaves thereof are divided into several leaflets and look like abird's foot. In the plant, green flowers are borne in spadices betweenMay and July, and the fruit is a red berry. The plant is used for thetreatment of phlegm, cough, palsy, epilepsy and the like.

Cervi cornus colla which is used in the present invention is a glutinousdrug prepared by boiling an antler. It has the effects of supplementingblood, stopping bleeding and stabilizing fetus and is used for lumbago,gonorrhea, leucorrhea and the like.

Phaseolus aureus which is used in the present invention grows well inloamy soil (black soil in which sand and clay are mixed at a suitableratio) in a mild climate. It grows a height of 30-80 cm. It is used totreat skin diseases and acts to lower fever and neutralize poison.

The antler velvet which is used in the present invention is the softantler of a deer and is used as a restorative for uplifting yang-qi andstrengthening muscle and bone.

The Trapa japonica fruit which is used in the present invention is thefruit of Trapa japonica which is an annual plant belonging to the familyTrapaceae. The root thereof is fixed in the mud, and the stem grows inwater in an elongated form, comes out of water and has a feather-shapedbase in water. The leaves are formed in a cluster at the top of thestep, are triangular in shape, and float on water, because the petiolehas protruded sacs containing air. In the plant, white flowers bloom insummer, and the fruit is an edible stone fruit. The plant grows in pondsor swamps and is distributed in Korea, Japan, China and others.

Brassica rapa which is used in the present invention is green-yellowvegetables belonging to the family Cruciferae, and is also called“vitamins” or “vitamin vegetables”, because it is rich in vitamins. Inthe plant, the content of carotene next to the effect of vitamin A istwo-times higher than in spinach. Thus, when 100 g of the plant iseaten, it provides 80% of the recommended daily value of vitamin A. Inaddition, the plant is also rich in iron and calcium.

Angelica acutiloba which is used in the present invention is the root ofan angelica plant which is a perennial plant belonging to the familyUmbelliferae. It mainly has anti-inflammatory and analgesic effects.

Citrus grandis osbeck which is used in the present invention is anevergreen short tree, reaches a height of 6 m and has thorns at thestem. The leaves are large in size and long oval in shape and have alength of 10-13 cm and a width of 4-5 cm. The leaf stalk has a length of1-2.5 cm, and the leaf axil is large in size and has a width of 0.4-1cm. The leaf has a serrate margin. The fruit is egg-shaped, has a lengthof 10-12 cm and a width of 9-10 cm and contains less than 6 chambers.The fruit generally weighs about 200 g, reaches a weight of 500 g in thecase of large fruits, and has some irregularities on the surface.

Circium japonicum which is used in the present invention is a perennialplant belonging to the family Compositae. The stem is upright, grows toa height of 50-100 cm and has cobweb-like hair together with white hair.The flowers bloom between June and August and are purple to red incolor. A head flower is formed at the branch and stalk end. The plant isused as a hemostatic agent.

Glycine semen germinatum is used in the present invention refers to amaterial obtained by germinating Glycine max Merrill belonging to thefamily Leguminosae. It is used for diplegia caused by moisture in thesummer season, limb trembling, bloated conditions caused by waterretention, and difficult urination. It is also used to lower the fevercaused by flu and to sweat.

Datura stramonium which is used in the present invention is an annualdicotyledonous plant belonging to the family Solanaceae of the orderTubiflorae. The stem is purple in color and spreads thick branches, andthe leaf stalk is long and has a non-uniform serrate margin. The corollais trumpet-shaped, light purple in shape and is surrounded by a tubularsepal. The end of the corolla is divided into 5 parts and has 5 stamensand 1 pistil. The fruit is a thorny capsule, and when it is ripe inOctober, it is divided into 4 parts to expose black seeds.

Zizyphus jujuba which is used in the present invention refers to ajujube fruit. The fruit has a red surface, is ovate and has a length ofabout 1.5-2.5 cm, and when it is ripe and turns red, it has a sweettaste. The fruit is eaten raw or dried after being harvested. The driedfruit is used in confectionary or for cooking or medicinal purposes. InChinese medicine, the dried fruit is used as diuretic, tonic andpalliative agents.

Dae-cheong-chow which is used in the present invention is the wholeplant of Hygrophila salicifolia (Vahl) Nees. belonging to the familyAcanthaceae and has a bitter taste and a cold nature. It is known totreat epidemic fevers and jaundice, reduce phlegm, stop coughing andtreat hemoptysis (Dictionary of Chinese Materia Medica). It containsabout 25 wt % of oil and a very small amount of alkaloid, calciumphosphate and calcium chloride.

Rheum undulatum which is used in the present invention is a perennialplant belonging to the family Polygonaceae, grows to a height of about 1m and is hollow. The leaf has a length of 25-30 cm. The flower bloomsbetween July and August, is used for medicinal purposes, has a coldnature and a bitter taste, and is used for difficult urination anddefecation, talking in delirium, sleeptalking, extravasated blood, etc.

Persicae semen which is used in the present invention refers a semen (arelatively large granule) contained in the peach seed. It is obtained bygathering the seed of a peach when the peach is ripe in July or August,breaking the hard seed shell, and taking out the semen contained in theseed. It is used for medicinal purposes in order to treat coughing,constipation and extravasated blood.

Aralia continentalis Kitagawa which is used in the present inventionrefers to aralia shoots and grows in mountains. It is about 1.5 m inheight and has hair at all the parts excluding the flower. The leavesare alternate and have a length of 50-100 cm and a width of 3-20 cm, andthe young leaves of the plant have a soft brown color. Small leaves ofthe plant are egg-shaped or oval and serrated at the margin. The leaveshave a green surface, and the backside of the plant is whitish. Theleaves have small cotyledons at both sides below the leaf stalk. Theplant is mainly used for muscular pain, headache, partial paralysis,etc.

Cordyceps militaris which is used in the present invention refers to acollection of mushrooms belonging to Clavicitipitaceae. It is present asan insect in the winter season and changes into a plant in summer. It isparasitic on the dead bodies of spiders, cicadas, butterflies, bees andthe like to produce fruit bodies. It includes Cordyceps militaris,Cordyceps sobolifera, etc.

Eucommiae cortex which is used in the present invention is a deciduoustree belonging to the family Eucommiaceae and grows to a height of morethan 10 m, and the leaves are alternate and ovate. In Chinese medicine,the cortex is used as a restorative and tonic and acts to strengthen thecerebral and cure lungs, knee pain and damping. In folk remedies, theboiled leaves are used for neuralgia and hypertension and also used astea.

Ephedra sinica which is used in the present invention is an evergreentree belonging to the family Ephedraceae of the order Ephedrales andgrows in dry elevated areas or sandy soil. It grows to a height of 30-70cm. The stem is upright and spreads many horsetail-like branches. It hasmany knobs, and a pair of scaly leaves are attached to each knob. Theroot is hard like a wood and is reddish brown. It functions asdiaphoretic, antipyetic, antitussive and diuretic agents and is used forthe treatment of fever and asthma.

Portulaca oleracea which is used in the present invention refers to apurslane and is used as feedstuff or medicine. It is soft, has a specialsmell, is viscous and has a salty taste and a cold nature. It has theeffects of alleviating fever, neutralizing poison and stopping bleeding,and thus is used for bacterial dysentery, swellings, piles, cervicallymphadenitis, eczema, leucorrhea, uterine hemorrhage, difficulturination, etc. It was reported that the plant has an antimicrobialaction, an action of increasing the peristalsis of intestinal tracts byincreasing the uterine smooth muscle contractility, and a diureticaction.

Rhododendron brachycarpum which is used in the present invention is anevergreen tree belonging to the family Ericaceae of the order Ericalesand grows in alpine regions. It grows to a height of 1-4 m. The treebark is grayish white. The leaves are alternate, but 5-7 leaves areclustered at the end of the branch. The leaves are ovate oroval-lanceolate and leathery in texture. The leaves have a length of8-20 cm and a width of 2-5 cm, and the leaf margin is plain andrevolute. The surface of the leaf is dark green, and soft brown hairgrows thick on the backside of the leaf. The leaves have a length of 1-3cm. It is used as a diuretic and tonic.

Codonopsis pilosulae radix which is used in the present invention is aclimbing perennial plant belonging to the family Campanulaceae of theorder Campanulales and discharges juice when being cut. The root issimilar to that of a balloon flower and has a length of about 30 cm. Theleaves are alternate, but opposite at the short branch, egg-shaped oroval and have fine hairs on both sides, and the backside thereof iswhite. The leaves have a length of 1-5 cm and a width of 1-3.5 cm, andthe leaf stalk has a length of 2-3 cm and is hairy.

The malt which is used in the present invention is a barley grainobtained by germinating unhulled barley under the action of moisture,heat and oxygen and is also frequently used to prepare a medium forculturing microorganisms. It contains saccharides, such as starch, andvitamins and is rich in amylase, and thus it is used as a nutritionalsupplement or a digestion aid (diastase, etc.) and sometimes used asfeedstuff or a raw material for preparing maltose.

Liriopis tuber which is used in the present invention is a monocotyledonplant belonging to the family Lilaeaceae of the order Liliales and growsin shade. The leaves come out from a short and thick rhizome to form acluster, and the root end becomes bigger like a peanut. The stem isupright and grows to a height of 20-50 cm. The leaves are dark green andlinear and have a length of 30-50 cm and a width of 8-12 mm, and thelower portion thereof becomes a leaf sheath. The flowers bloom betweenMay and June and are purple, and 3-5 flowers are attached to each knobin spikes. It is used as anti-inflammatory, tonic, antitussive,expectorant and cardiotonic agents.

The Chaenomeles Sinensis fruit which is used in the present invention isthe fruit of Chaenomeles Sinensis and has a sour taste and a warmnature. It is used for a disturbance in muscular extension andcontraction, beriberi, and vomiting and diarrhea.

Akebiae caulis which is used in the present invention is the stem ofAkebia quinata Decaisne or other plants and is obtained by peeling theplant and cutting the peeled plant in a width direction. It is used forascites caused by pyelonephritis, cystitis and urethritis, oraleruption, red urine, paralytic pain, etc.

Saussurea lappa which is used in the present invention is a perennialdicotyledonous plant belonging to the family Compositae of the orderCampanulales, and the stem is upright and grows to a height of 0.8-2 m.Hair grows thick throughout the plant, and the plant is used formedicinal purposes. The leaves are alternate, oval or long oval in shapeand serrated at the margin, and hair grows thick on the backside of theleaf. The flowers bloom between July and August, have a diameter of 5-10cm and are yellow, and a head flower is attached to each leaf axil. Itis used as diaphoretic, diuretic and expectorant agents and containsanthelmintic components.

Mui which is used in the present invention refers to the ripe driedfruit of Ulmus macrocarpa belonging to the family Ulmaceae and is alsocalled “Mu-go”, “Mui-in” or “U-mui” in Korean. It is used forenterohemorrhage, piles, malignant swellings, etc.

Moutan cortex radicis which is used in the present invention refers tothe root cortex of Paeonia suffruticosa and is used for menstrualirregularity, menstrual cramps, a bruise, hemoptysis, nose bleeding,bone ache caused by ischemia, blood pressure elevation, extravasatedblood, injuries, inflammation, swellings, initial appendicitis, etc.,and eliminates breast discomfort. Also, it was reported that the planthas analgesic, sedative, antipyretic, anticonvulsant, anti-inflammatory,antithrombotic, anti-allergic, gastric juice secretion-inhibiting anduterine bleeding-inhibiting effects and antibacterial effects.

Mentha arvevsis which is used in the present invention is a perennialdicotyledonous plant belonging to the family Lamiaceae of the orderTubiflorales and is called “Park-ha”, “Ya-sik-hyang”, “Bun-ha-chae”,“In-dan-chow” or “Ku-bak-ha” in Korean. It grows in moist fields to aheight of 60-100 cm. The stem is rectangular in section and hairy on thesurface. The leaves are alternate simple leaves with stalks and serratedat the margin.

Bang-pung which is used in the present invention is a medicinal materialmade using the root and rhizome of Saposhnikovia divaricata Schiskinbelonging to the family Umbelliferae. It means preventing “pung”(paralysis) and is very important in treating paralysis. It iscylinder-shaped and the lower potion is slightly slender. The outersurface thereof is light brown in color, and the upper portion of therhizome has dense vertical wrinkles. In some cases, a brown hairy leafsheath is attached to the plant. It is effective against all kinds ofparalysis-associated conditions, including headache, chill, fever,systemic pain, and throat pain.

Pinellia ternata which is used in the present invention is a perennialplant belonging to the family Araceae of the order Arales and grows infields to a height of about 30 cm. Although the bulb is toxic, but inChinese medicine, the plant has expectorant and antitussive effects, andthus is used for vomiting, diarrhea, and vomiting during pregnancy.

Chinese cabbage which is used in the present invention is a biennialplant belonging to the family Cruciferae of the order Papaverales. Theouter leaf is inverted-egg shape, has a white vein at the center of theleaf and is green or light green. 100 g of Chinese cabbage contains 33IU vitamin A, 100 IU carotene, 0.05 mg vitamin B□, 0.05 mg vitamin B₂,0.5 mg nicotinic acid, and 40 mg vitamin C. Vitamin A is deficient inthe white portion and abundant in the green portion.

Bak-gul-chae which is used in the present invention refers to theabove-ground portion of Chelidonium majus Linne belonging to the familyPapaveraceae. Opposite leaves are attached to the stem having a numberof branches, and the stem is hollow and light brown in color. The wholebody of the plant discharges a dark-yellow liquid gel. It was reportedto the plant has an anticonvulsant effect, the effect of promoting theperistalsis of intestinal tracts and the secretion of saliva, ananti-tumor effect, an anti-hepatitis effect and an antibacterial effect.

The Pulsatilla Koreana root which is used in the present inventionrefers to the root of Pulsatilla koreana Nakai or others belonging tothe family Ranunculoideae. The root is cylindrical in shape, and theouter surface is yellowish brown or brown and has irregular verticalwrinkles. The epidermis is easily detached to expose a yellow xylem, andthere is a net-shaped pattern. The root crown is covered with white softhair and has the stem and leaf positions. The root is hard and crumbly,and thus easily broken, and the broken surface is smooth. It is used fordysentery caused by moist heat, amoebic dysentery, cervicallymphadenitis, and bleeding caused by piles.

Cynanchi radix which is used in the present invention refers to the rootof Cynanchum atratum Bunge or other plants belonging to the familyAsclepiadaceae. In the plant, light-yellowish elongate roots areclustered at short rhizomes to form a bridle shape and are brittle, andthe broken surface is white in color. The cortex is distinguished fromthe xylem. The root is used to lower the fever of blood to treatconditions in which a slight fever at the late state of fever disease orafter childbirth is not removed due to the exhaustion of Qi-vessel andin which the body is languid. In addition, the root is used to treat acough caused by fever and pulmonary fever, difficult urination,swellings, malignant boils, sore throat, and snake bites.

The Bletilla striata tuber which is used in the present invention is amedicinal material obtained by drying the tuber of Bletilla striatabelonging to the family Orchidaceae. It is a hemostatic agent which isused for blood spitting caused by pulmonary fever and blood vomitingcaused by gastric fever, and it is applied to an external wound in apowdered state. It is used for surgical diseases such as boils and actsto granulate. It was reported that the tuber has various pharmacologicaleffects, including stopping local bleeding, treating stomach andduodenum, inhibiting bacteria and increasing blood pressure, as well asanticancer activity.

Santalum album which is used in the present invention is an evergreenbroad-leaved tree belonging to the family Santalaceae, grows to a heightof 6-10 m and is blue green in color and glossy. The leaves are oppositeand egg-shaped. The inside of the tree is yellowish, emits a sweetfragrance and is used in incense burners, drugs, handiworks, etc.

The Ampelopsis japonica root which is used in the present inventionrefers to the root of Ampelopsis japonica. It is used to treat poisonand a burn.

White Poria cocos which is used in the present invention refers to thedried sclerotium of Poria cocos. It grows on places from pine trees havebeen cut out, and it is also cultivated. It is parasitic on the root ofred pine trees, has a sweet and stale taste and a mild nature. Also, itacts as a supplement and has a diuretic effect which is not strong. Ithas been used as a tonic, acts in the lung, spleen, heart, nerve andbladder meridians to protect the spleen, alleviates phlegm andstabilizes the spirit. According to the results of pharmacologicalexperiments, it was found that the white Poria cocos has a diureticeffect, a blood glucose lowering effect, a sedative effect and animmunity activating effect.

Aconitum koreanum which is used in the present invention grows in grassfields or forests. The root is strongly poisonous, but in Chinesemedicine, it is used as antispasmodic and analgesic agents.

Thujae orientalis semen which is used in the present. invention refersto the seed of the Thujae orientalis fruit. It acts to stabilize thebody and sprit and lubricate the intestines, and thus is used forpalpitation, perspiration, constipation, etc.

Hedyotis diffusa which is used in the present invention refers to thewhole plant of Oldenlandia diffusa (Willd.) Roxburgh belonging to thefamily Rubiaceae. In the plant, white flowers resembling the lingua ofsnakes bloom. It is an annual plant and called “Baeg-wha-sa-seol-cho” or“Baeg-un-pul” in Korean, because it was collected for the first time inBaegun Mountain, Jeollanam-do, Korea. It grows wild mainly in southernregions and Jeju-do, Korea. It is used for a cough caused by pulmonaryfever, tonsillitis and a sore throat. In addition, it is also used forappendicitis, pelvic inflammatory disease, icteric hepatitis anddysentery and acts to treat boils and neutralize snake venom.

Paeonia japonica which is used in the present invention is a perennialplant belonging to the family Ranunculaceae. It grows in the deep recessof mountains and grows to a height of 45-50 cm. The root is used asanalgesic and antispasmodic agents and for women's diseases.

The Angelica dahurica root which is used in the present invention refersto the root of Angelica dahurica. It is used for a headache or lumbagocaused by flu, paranasal sinitis and the like. It is also used to treatboils.

The Atractylodes macrocephala rhizome which is used in the presentinvention is a medicinal material obtained by removing the rhizome orintegument of Atractylodes macrocephala and drying the removed rhizomeor integument. It has a special odor, is slightly bitter and sweet intaste, is viscous when being chewed, and has a warm nature. It is usedfor light eating caused by a weak stomach, languor, facial yellowing,discharge of loose feces, and diarrhea. In addition, it facilitateswater excretion when the whole body is swelled and digestion isdifficult due to water retention. Also, it is used for coughing andclear phlegm, a flu involving gastrointestinal disorders, and limb pain.

The Rubus coreanus fruit which is used in the present invention is theunripe fruit of Rubus coreanus belonging to the family Rosaceae. It isodorless and has a sour and sweet taste and a warm nature. It enhancesthe renal function and is used for involuntary emission of semen and awet dream. Also, it is used for reduced visual acuity and makes the hairblack. Furthermore, it also makes the skin smooth and beautiful. It wasreported that the fruit has anti-inflammatory, antioxidant andanti-Helicobacter pylori effects.

Poria cocos which is used in the present invention is a mushroombelonging to the family Polyporaceae, the order Aphyllophorales, theclass Basidiomycetes, and is parasitic on the root of trees such as pinetrees in soil. It has a sclerotium size of 10-30 cm and is round-shaped,longish or mass-shaped. The surface is reddish-brown, light brown ordark brown in color and is generally rough, and in some cases, the rootbark is broken. The fresh is white and gradually turns rose pink. It isclassified, according to color, into white Poria cocos and red Poriacocos. Also, a portion part of Poria cocos that the pine tree rootpenetrates is called “Bok-sin” in Korean. It has tonic, diuretic andsedative effects and I used for renal disease, cystitis and urethritis.

Arecae pericarpium which is used in the present invention refers to thepeel of the ripe fruit of Areca catechu L. belonging to the familyArceaceae and is distributed in Korea, China, Japan and others. It hasan hollow pyramidal shape or a shape obtained by cutting a long ovalbody in a vertical direction. The outer surface is yellowish brown incolor, has vertical wrinkles and is covered with a thin fiber layer. Theinner surface is brown or dark brown in color and glossy and hasvertical fine wrinkles. The cut surface is fibrous, and thecross-section is light yellowish brown in color. When viewed with amagnifying glass, the fiber group is shown as a light brown or darkbrown point. It has other Korean names, including “Jeo-bin-rang”,“Bin-rang-pi”, “Bin-rang-gak”, “Bok-mo”, “Dae-bok-yung”, and“Dae-bok-bin-rang”, “Dae-bok-mo”.

Aconiti radix which is used in the present invention refers to the tuberroot of Aconitum japonicum belonging to the family Ranunculaceae and isalso called “Aconiti tuber”. In Chinese medicine, it is not used aloneand is used in combination with Cinnamomum cassia, Poria cocos orlicorice root as stimulant, cardiotonic, analgesic and diuretic agents.It is used to alleviate a cold sweat, a chill, paralysis, pain,neuralgia and rheumatoid arthritis, in addition to restore an extremelyreduced metabolic function.

Allium tuberosum which is used in the present invention is a perennialplant belonging to the family Lilaeaceae. The bulb has a short rhizomeat the lower portion and a blackish yellow fiber at the outside. Thebulb is used to make the stomach strong and treat a burn, and a softportion is used for eating purposes. The seed is called Allii tuberosisemen and used for urination in Chinese medicine.

Ostericum sieboldii which is used in the present invention grows in agrass field to a height of 40-70 cm. The plant contains saponin andfatty oil in the root, and thus is used to an antipyretic, analgesic ortonic and as a medicinal material for respiratory, digestive andcardiovascular diseases.

Borneol which is used in the present invention refers to a crystalobtained from borneo camphor. It is aromatic and is used to treatparalysis, congestion, a confused mind caused by fever, or a sourthroat.

Sa-kwa-rak which is used in the present invention refers to thereticular fiber and vascular bindle of the fruit of Luffa cylindricaRoemer belonging to the family Cucurbitaceae. When the plant is ripe,the flesh becomes fibrous. The medicinal material is long cylindrical orlong rhombic in shape, slightly bent, and relatively slender at bothends. The outer surface is white or yellowish white in color, andseveral layers of reticular fiber are entangled to form a net-likestructure. The medicinal drug is lightweight, has a hard texture and isnot easily broken off. The cut side has 3 ovaries having three largecavities in which some black seeds may remain. It is also called“Man-kwa” in Korean. It was reported that the medicinal material has theeffects of inhibiting edema in arthritis, inhibiting inflammation inerythema, relieving pain and inhibiting skin bacterial infection.

Adenophorae radix (“Sa-sam”) which is used in the present inventionrefers to the root of Adenophora triphylla var. japonica Hara or otherplants belonging to the family Lilaeaceae and is known as one of fiveginsengs along with “In-sam” (ginseng), “Hyun-sam”, “Dan-sam” and“Ko-sam”, because they are used for similar therapeutic proposes, eventhough they are processed in different ways. The “Sa-sam” was namedbecause it is white in color and grows well in sandy soil. It ispyramidal or long conical in shape and bent, and has branched roots insome cases. The upper portion has a rhizome having vertical wrinkles.The root is lightweight and is likely to break off, and the brokensurface is milky and has many pores. It was reported to have variouspharmacological effects, including expectorant, antibacterial, hemolyticand cardiotonic effects.

Wild ginseng which is used in the present invention is a kind of ginsenggrowing naturally in the deep recesses of mountains. It is sweet andslightly bitter in taste and has a slightly warm nature. It enters thespleen and ling meridians to strengthen vigor.

Crataegus pinnatifida fruit which is used in the present invention is amedicinal material obtained by drying the ripe fruit of Crataeguspinnatifida Bunge var. typica Schneider belonging to the familyRosaceae. The fruit has an apple taste and is red as in the case of asmall apple. It has a shape similar to that of a red jujube fruit. Itwas reported to have a cardiotonic effect, a blood circulation improvingeffect and a blood pressure lowering effect.

The Cornus officianalis fruit which is used in the present invention isthe fruit of Cornus officianalis. The fruit is separated into a freshand a seed, and the separated fresh is used as a raw material forpreparing alcoholic drinks, tea and a Chinese medicine. In Chinesemedicine, the fresh is used for headache, tinnitus and a lung troubleand as an antipyretic, and in folk remedies, it is used for a cold sweatand enuresis.

Dioscorea rhizoma which is used in the present invention is the tuberroot of Disocorea japonica or Disocorea batatas belonging to the familyDisocoreaceae. It is obtained by gathering the root between the 18^(th)of the 24 seasonal divisions and the winder solstice and drying thecollected root. The outer surface is white or yellowish brown in color,and the inside consists of a powdered tissue or a gelatinized hornytissue.

Zizyphi spinosi semen which is used in the present invention is the seedof Zizyphi spinosi. It is used for hypersensitivity, insomnia,forgetfulness, a cold sweat and the like and has the effects ofstrengthening a stomach and inhibiting anemia. It was reported that themedicinal material has various pharmacological effects, includingsedative, sleeping, blood pressure-lowering, analgesic, antioxidant,immunity boosting and uterus exciting effects.

Gardenia fruit which is used in the present invention is the fruit ofGardenia jasminoides and is used as antipyretic, hemostatic and diureticagents.

Saururus chinensis which is used in the present invention is a perennialdicotyledonous plant belonging to the family Saururaceae of the orderPiperales and grows in damp ground. The rhizome is white and spreadssideways in mud. The stem is 50-100 cm in height. The leaves arealternate, egg-shaped, 5-15 cm long, sharp at the end, heart-shaped atthe base, has 5-7 veins and are plain at the margin. The leaf surface isgreen, and the backside of the leaf is light white, but 2-3 leaves atthe top of the stem have a white surface. The leaf stalk is 1-5 cm inlength and has a broad base covering the stem. The plant is used whenthe body is swelled and the urine is not easily discharged. In addition,it is also used for beriberi, jaundice, hepatitis and the like.

Atractylodes japonica Koidzumi which is used in the present invention isa perennial dicotyledonous plant belonging to the family Compositae ofthe order Campanulales. The rhizome is thick, long, knotty and fragrant.The stem is upright, branched into several parts at the top and grows toa height of 30-100 cm. The leaves sprouting from the root are dried outwhen the flowers bloom. The leaves attached to the stem are alternate,the leaves attached to the base of the stem are divided into pieces, andthe divided pieces are 3-5 in number, egg-shaped or inverted-egg shaped,glossy at the surface, white at the backside and serrated at the marginand have leaf stalks having a length of 3-8 cm. The leaves attached tothe top of the stem are not divided and have no leaf stalk. The rhizomeis used as a medicinal material called “chang-chool”. It has diureticand analgesic and stomach-strengthening effects, and thus is used forinappetence, indigestion, gastritis, flu and the like.

Sang-gi-saeng which is used in the present invention is a medicinalmaterial obtained by drying the leaf, stem and branch of Loranthusparasticus Merr. or Viscum album L. var. coloratum Ohwi belonging to thefamily Loranthaceae. It is has a blood pressure-lowering effect, andthus is used for dizziness caused by hypertension. In addition, itstrengthens the liver and the kidneys to strengthen bone and muscle andis used to treat the instability of fetal movement.

Mori cortex radicis which is used in the present invention refers to therhizome of Morus alba and similar plants. It is used to treat a coughcaused by pulmonary fever, and asthma, and has a diuretic effect. It isused to treat acute pyelonephritis and edema, has a blood pressurelowering effect and is also used for nasal hemorrhage and bloodspitting. In addition, it is also used to treat epidemic hepatitis. Itwas reported to have various pharmacological effects, includingantitussive, diuretic, blood pressure-lowering, sedative, analgesic,antipyretic, antispasmodic and antimicrobial effects.

Dichroa febrifuga which is used in the present invention is adicotyledonous deciduous shrub belonging to the family Rutaceae of theorder Geraniales and grows in mountainous districts. It grows to aheight of 1.5-3 m, and the bark is grayish brown in color, and youngbranches are slightly hairy. The leaves are alternate, 5-13 cm long,ovate or inverted-egg shaped, sharp at the end and smooth or serrated atthe margin. The leaf surface is yellowish green and glossy and has aunique smell and a short stalk. The root is used as a medicinal materialcalled “chi-shin-yang” to treat the cough, fever and sour throat causedby flu and has effects on arthritis, dysentery, swellings and malaria.

The Morus alba leaf which is used in the present invention is the driedleaf of Morus alba L. or other plants belonging to the family Moraceae,and the young leaf of the plant is also called “sang-ji” in Korean.Morus alba (mulberry) which is eaten by silkworms has excellent effects,like a tree sacred to the gods. The Morus alba leaf is used to treatfever, headache, eyeball hyperemia, cough, thirst, skin hives and thelike.

precatorius which is used in the present invention is called“Sang-sa-ja” or “Hong-doo” in Korean. It is used as arrow poison,because the shell contains highly toxic abrin. The leaf containsglycyrrhizin and is sweet like licorice, and thus is used to preparebeverages.

The rhizome of ginger which is used in the present invention is dried,crushed and used as spice in bread, confectionary, curry, sources andpickle. Also, after the rhizome is peeled and boiled, it is preserved insyrup and used to prepare ginger tea and ginger alcoholic beverages. InChinese medicine, the dried rhizome has effects on indigestion, vomitingand diarrhea, promotes blood circulation and has anti-inflammatory andanalgesic effects.

Rhizoma acori graminei which is used in the present invention is aperennial dicotyledonous plant belonging to the family Araceae of theorder Arales and grows in mountainous districts or a riverside of afield. The rhizome spreads sideways, and the fibrous roots sprout fromthe knobs. The distance between the knobs in soil is long, but theabove-ground part has a short distance between the knobs and is green incolor. The leaves sprout from the rhizome in a cluster, is 30-50 cmlong, stripe-shaped, has no vein and is sharp at the end. The base ofthe outer leaf surrounds the base of the inner leaf, and the leaves arealternately arranged in two rows. The rhizome is used as analgesic,sedative and stomachic agents, and in folk remedies, is also added to abath.

Agrimonia pilosa ledebour which is used in the present invention is aperennial plant belonging to the family Rosaceae. In Chinese medicine,the whole plant is dried between the summer and the fall but beforeflowering and is used as hemorrhage and convergent agents and to treatuterine bleeding, poison, blood vomiting, urine bleeding, carbuncle,cancer, etc.

Seol-kyun-cho which is used in the present invention is the root ofSalvia plebeian R.Br. belonging to the family Labiatae. It is bitter andhot in taste. It has the effect of alleviating swellings and is known tobe effective in treating blood vomiting, nasal bleeding, a bruise,poison, etc.

Se-shin which is used in the present invention is a medicinal materialobtained by drying the root of Asarum sieboldii which is a perennialplant belonging to the family Aristolochiaceae. The root is gatheredbetween the spring and the summer, washed clean with water and dried inshade. The dried root is used for headache, nasal stuffing, fever,phlegm and breathlessness, which result from flu. It is used to treatlaryngitis, nasitis and bronchitis.

Perilla frutescens var. acuta which is used in the present invention isan annual plant belonging to the family Lamiaceae. It grows to a heightof 30-100 cm, and the leaves are opposite, egg-shaped and serrated atthe margin. Between August and September, light purple flowers bloom atthe leaf axil or stem end, and the fruit is a round achene. The leaf andstem are used for medicinal purposes, and the young leaf and seed areused for eating purposes. The plant is also called “So-yup”, “Cha-zo-gi”or “Cha-ze-gi” in Korean, and the seed is called “So-ja” in Korean.

Pinus densiflora which is used in the present invention is an evergreenconifer tree belonging to the family Pinaceae. The leaves are used forberiberi and indigestion and as a tonic, and the flowers are used fordysentery. The rosin is used as a raw material for preparing a plaster.

Jasminum floridum root which is used in the present invention refers tothe root of Jasminum floridum Bge. belonging to the family Oleaceae andis used to treat wounds.

Anethum graveolens which is used in the present invention is an annualplant belonging to the family Umbelliferae. Because all parts of theplant emit a unique fragrance, the flower, leaf, stem and seed of theplant are used for medicinal purposes. The seed has excellent digestive,carminative, sedative and sleeping effects and is effective in removingfoul breath and preventing arteriosclerosis. The use of the seed as apillow enables a person to sleep well.

Euphorbia lathyris seed which is used in the present invention is theseed of the medicinal plant Euphorbia lathyris. The residue remainingafter removing oil from the seed is used as diuretic and laxative agentsand to treat edema, ascites and food poisoning. The seed is highlytoxic, and thus requires care in use.

Dipsacus asper which is used in the present invention is a perennialdicotyledonous plant belonging to the family Labiatae of the orderTubkflorales and grows in mountainous districts. The stem is upright andabout 1-m high and has fine hair throughout thereof, and about 5pyramidal thick tuber roots sprout from the stem. The leaves areattached opposite to each other, have long stalks and are heart-shapedor egg-shaped. The leaves are regularly serrated at the margin and havefine hair at the backside. The thick root is used to treat a cut andwomen's diseases.

Tricholoma matsutake is a typical edible mushroom belonging to thefamily Tricholomataceae, grows on soil in a pine-grove and has a uniquefragrance and a good taste. Generally, Tricholoma matsutake occurs on20-60-years old pine-groves and is a symbiotic fungus forming mycorrhizain a state attached to the rootlets of a pine.

Cimicifuga heracleifolia which is used in the present invention is aperennial plant belonging to the family Ranunculaceae. In Chinesemedicine, the root of the plant is used as antipyretic and antidoteagents. It was reported that, when the seed is used to lower a fevercaused by flu, the fever is lowered while sweating.

Bupleurum falcatum which is used in the present invention is a perennialdicotyledonous plant belonging to the family Umbelliferae of the orderUmbellales. The root contains saponin, fatty oil and the like, and inChinese, it is used as antipyretic, analgesic and tonic agents or totreat respiratory, digestive and cardiovascular diseases.

Massa medicata fermentata which is used in the present invention iscalled “Yuk-sin-kok” in Korean and refers to a material prepared bymixing 6 kinds of medicinal materials. It improves the function ofrespiratory organs, facilitates digestion and acts to make the stomacheasy. It is effectively used when a person suffers from indigestion,when a person feels heavy in the chest, when vomiting and diarrhea occurand when a person has a stomachache. The results of pharmacologicalexperiments revealed that the plant has the effect of strengthening thestomach.

Artemisia leaf which is used in the present invention refers to amedicinal material obtained by drying the leaf or young stem ofArtemisia argyi, Artemisia princeps or Artemisia mntana. It makesQi-blood and meridians warm, and thus is effective in retarding uterinebleeding occurring when the uterus and the abdominal region are cold andweak, bleeding during pregnancy, blood vomiting, nasal bleeding andblood spitting. Also, it is used for conditions in which the lower bellyabove the bladder is weak and cold and the abdomen is cold and has pain,and for menstrual irregularity and lecorrhea. In addition, it iseffective in treating eczema and itching. It was reported that the planthas various pharmacological effects, including a hemostatic effect, anantibacterial effect, a bronchial smooth muscle-relaxing effect, anexpectorant effect, a sleeping effect, a uterus excitation-inductingeffect, and an anaphylatic shock-preventing effect.

Yakssuk which is used in the present invention refers to a wormwoodrequired for performing moxibustion and a wormwood for medicinalpurposes. In Chinese medicine, the leaf of wormwood is used as amedicinal material called “Ae-yeop” and acts to stop bleeding andinhibit the growth of bacteria and as an expectorant. Also, it iseffective against menstrual pain, menstrual irregularity and leucorrhea.A solution obtained by boiling Yakssuk in water is used to wash theaffected part of persons having eczema or itching.

Lespedeza cuneata which is used in the present invention is adicotyledonous shrub belonging to the family Leguminosae of the orderRosales and is called “Ya-Kwwan-moon”, “No-woo-keun”, “Ho-ji-ja”,“San-chae-ja” or “Bi-su-ri” in Korean. It is used for poor vigor,impotence, premature ejaculation, cough, pertusis, and snake bites. Itwas reported that the plant has various pharmacological effects,including an expectorant effect, an asthma-relieving effect, an effecton the uterus, an antibacterial effect, etc.

Polygonum multiflorum stem which is used in the present invention refersto the stem of Polygonum multiflorum which is a perennial climbingdicotyledonous plant belonging to the family Polygonaceae of the orderPolygonales. It is effective as antitussive and expectorant agents andagainst arthritis.

Houttuynia cordata which is used in the present invention refers to theabove-ground part of Houttuynia cordata belonging to the familySaururaceae. It has excellent antipyretic and wound-draining effects,and thus is used for a cough, bloody pus, pneumonia, acute and chronicbronchitis, enteritis, urinary tract infection, high fever, anddifficult urination. It was reported that the plant has variouspharmacological effects, including antibacterial, immunity-boosting,anti-inflammatory, diuretic and antitussive effects.

Forsythia fruit which is used in the present invention refers to thefruit of Forsythia viridissima or Forsythia suspensa belonging to thefamily Oleaceae. The fruit lowers fever and neutralizes poison, and thusis used to lower the fever of the heart in the initial stage of diseaseand used for high fever and numbness. Also, it is used for boils, redspots, typhlitis, lung abscess, lymphadenitis, a sore throat, etc., andhas diuretic and anti-inflammatory effects. It was reported that theplant has various pharmacological effects, including antibacterial,anti-inflammatory, blood pressure-lowering, hemostatic, liver-treating,antipyretic effect, antiemetic and diuretic effects.

Nelumbinis semen which is used in the present invention refers to thefruit of a lotus flower. It is used for women's diseases.

Nelumbo nucifera seed which is used in the present invention is the seedof a lotus flower and refers to a medicinal material obtained by peelingthe seed and drying the peeled seed. The dried seed has been widely usedfor a long period of time, because it has been known that it strengthensa stomach and raises sprit and vigor and that the internal use of theseed reduces the body weight, prevents aging, does not feel hungry andincreases the length of life. It was reported that the dried seed hasthe effect of inhibiting nasal cancer and throat cancer.

Litchi chinensis which is used in the present invention is native to thesouthern part of China and is frequently cultivated as a fruit tree. Thefruit is round and about 3-cm diameter, and the outer surface hasprotrusions and resembles the turtleback surface. The fruit flesh issour and sweet, has a unique fragrance and is eaten raw. In the southernpart of China, the fruit is known as the king of fruits.

Papaver somniferum flower which is used in the present invention refersto the flower of a poppy. In folk remedies, the fruit and plantseparated from Papaver somniferum have been used for emergent diseases.When a person smokes opium together with tobacco, the person feelsdimness, and when the person habitually smokes opium, poisoning withopium appears, leading to death in severe cases. The seed has a fatcontent of 45-50%, and thus is used for edible or industrial purposes.The seed contains no anesthetizing component.

Ganoderma lucidum which is used in the present invention is asemicircle-shaped, kidney-shaped or fan-shaped mushroom. In Chinesemedicine, the mushroom is used for nervous breakdown, hypertension andvarious cancers, because it has tonic, antitussive and tumor-relievingeffects. The mushroom is covered with a hard shell and glossy, as if itis vanished. Thus, it is valuably used as a Chinese medicinal materialand also used for decorative purposes.

Aconiti radix which is used in the present invention refers to the tuberroot of Aconitum japonicum belonging to the family Ranunculaceae and isalso called “Aconiti tuber”. In Chinese medicine, it is not used aloneand is used in combination with Cinnamomum cassia, Poria cocos orlicorice root as stimulant, cardiotonic, analgesic and diuretic agents.It is used to alleviate a cold sweat, a chill, paralysis, pain,neuralgia and rheumatoid arthritis, in addition to restoring anextremely reduced metabolic function.

Acanthopanax sessiliflorus bark which is used in the present inventionrefers to the bark of the root, stem and branch of Acanthopanaxsessiliflorus or other plants belonging to the family Araliaceae. Itenhances the energy of the liver and kidneys to strengthen muscle andbone. Thus, it is used for limb paralysis and convulsion, weak waist andknee, impotence of the lower limbs, a bone fracture, a bruise, edema,etc. It was reported that the bark has various pharmacological effects,including immunity-boosting, antioxidant, anti-fatigue, anti-fever,anti-stimulant, endocrine function-regulating, bloodpressure-regulating, anti-radioactive and poison-neutralizing effects.

Schizandra chinensis fruit which is used in the present invention refersto the fruit of Schizandra chinensis. It has a diameter of about 1 cmand is dark red and ball-shaped. It contains red juice and 1-2 reddishbrown seeds. It has five tastes, sweet, sour, bitter, salty and hottastes, and among these tastes, the sour taste is the strongest. Itcontains shisandrin, gomisin, citral, malic acid, citric acid and thelike, and thus is used to strengthen the heart, lower blood pressure andincrease immunity and as a tonic. It acts to enhance lung functions andhas antitussive and expectorant effects, and thus it is effective intreating a cough or thirst.

Chinensis Galla refers to an insect wax resulting from a process inwhich Schlechtendalia chinensis belonging to the family Aphididae of theorder Homoptera is parasitic on the leaf of Rhus javanica belonging tothe Anacardiaceae. It has an irregular bag shape and frequentlyresembles the human ear. It is hollow and very sour in taste. In Chinesemedicine, it is used for the treatment of diarrhea, anal prolapse,gastric ulcer, duodenal ulcer, involuntary emission of semen, hemafeces, haematuria, stomatitis, etc., because it has convergent,hemostatic and antibacterial effects. It has a tannin content of 50-60%,and thus is used as a raw material for preparing coloring agents or ink,in addition to tanning agents.

Evodia officinalis which is used in the present invention is adicotyledonous deciduous tree belonging to the family Rutaceae of theorder Geraniales. In Chinese medicine, a material obtained by gatheringthe unripe fruit of Evodia officinalis in September and drying thegathered fruit is used as stomachic, anthelmintic, antidotal anddiuretic agents.

Linderae radix which is used in the present invention is the dried tuberroot of Lindera strichnifolia. It promotes Qi circulation, eliminatescold effects and makes the bladder and kidneys warm, and thus is usedfor the treatment of cardio-abdominal pain, beriberi, urinaryincontinence and the like.

Maydis stigmata which is used in the present invention refers to cornsilk in Chinese medicine. It is used for adult diseases, includingdiabetes, hypertension and hypercholesterolemia, difficult urination,acute gastritis, nephritis, edema in pregnant women, inflammation,fever, hemorrhage, a calculus, pleurisy, ascites, cystitis, urethritis,jaundice, hepatitis, cholecystitis, cholangitis, cirrhosis, arthritis,etc.

Polygonatum odoratum root which is used in the present invention refersto the dried root of Polygonatum odoratum and has the effects ofclearing away fever and improving female vigor (Yin-Qi).

Orostachys japonicus which is used in the present invention is aperennial dicotyledonous plant belonging to the family Crassulaceae ofthe order Rosales and grows on or around rocks in mountains. The wholeplant is medicinally used as a tonic, and the squeezed juice is used forinsect bits or burns. It has an anticancer effect, is used asantipyretic and hemostatic agents and is effective in treatinghepatitis, eczema, dysentery, malignant tumors, and burns

Solani nigri herba which is used in the present invention is an annualdicotyledonous plant belonging to the family Solanaceae of the orderTubkflorales. In Chinese medicine, the medicinal material is obtained bycollecting and drying the whole plant between the summer and the falland is used to treat flu, chronic bronchitis, nepthritis, jaundice,boils, cancer, etc. In folk remedies, the pulverized raw plant isapplied to wound sites, or the boiled raw plant is used to wash affectedparts.

Gentiana scabra BUNGE which is used in the present invention is aperennial plant belonging to the family Gentianaceae. It is used for thetreatment of jaundice caused by the damp heat of the liver and gall,dysentery, itching of the secret parts, leucorrhea, eczema, limbconvulsions caused by high heat, cheek pain, headache, eye hyperemia,hard hearing, etc. It was reported that the plant has variouspharmacological effects, including the effects of protecting liverfunctions, promoting bile secretion and inhibiting Pseudomonasaeruginosa, modified bacteria, Diplococci, Staphylococcus aureus, etc.

Euphoria longana testa which is used in the present invention refers thetesta of Euphoria longana belonging to the family Sapindaceae. It has asoft texture, is viscous and has a sweet taste and a unique fragrance,and thus is also used as an accompaniment to a drink. Furthermore, it isused for irregular heart beating caused by too much thinking,forgetfulness, insomnia, indigestion, and discharge of loose feces. Inaddition, it is used for convalescent weakness, weariness,uncontrollable sweating, stagnation of Qi aand blood after childbirth,and edema. The pharmacological effects of the plant include a fungaldermatitis inhibitory effect, a tonic effect, an antioxidant effect, animmunity-activating effect, etc.

Achyranthes japonica root which is used in the present invention refersthe root of Achyranthes japonica Nakai belonging to the familyAmaranthaceae. It is substantially odorless and is viscous. It isslightly sour in taste and has a mild taste. When it is used raw, iteliminates extravasated blood and boils, and when it is used afterboiling, it strengthens the liver and kidneys to strengthen muscle andbone. Because it eliminates extravasated blood, it is used for menstrualirregularity and abdominal pain after childbirth, supplements marrow,and promotes Yin-Qi circulation to alleviate arthritis and treat themouth and tongue rash caused by the deficiency of Yin-Qi. In addition,it was reported that the plant has various pharmacological effects,including a uterus exciting effect, a cholesterol-lowering effect, adiuretic effect, a blood glucose-lowering effect, and a liverfunction-improving effect.

Polygalae radix which is used in the present invention refers to theroot of Polygala tenuifolia which is a perennial dicotyledonous plantbelonging to the family Polygalatenuifolia of the order Geraniales. InChinese medicine, it is used as expectorant, tonic and aphrodisiac.

Genkwa flos which is used in the present invention refers to the bud ofDaphne genkwa belonging to the family Thymelaeaceae and is called“Geo-soo” or Doo-tong-hwa” in Korean. It is used to treat asthma and acough, allows the water in the side to come down, and treat dropsy. Inaddition, it is used to treat abdominal distension, boils, headeruption, difficult urination, constipation, etc. It was reported thatthe plant has the pharmacological effects of promoting urination,inhibiting the movement of the intestinal tract and uterine and killinginsects.

Oenothera odorata which is used in the present invention refers to anevening primrose. The root is used as a medicinal material, and for somediseases, the leaf is also used. In folk remedies, the seed oil is alsoused for diabetes. The root has antipyretic and anti-inflammatoryeffects and is effective in treating flu, a sour throat, bronchitis anddermatitis. The seed oil is effective against diabetes, hypertension andobesity, and it inhibits the excessive accumulation of lipids, includingcholesterol, and thus is used for hyperlipidemia.

Clematis mandshurica root which is used in the present invention refersto the root of Clematis mandshurica. In Chinese medicine, the root isused for gout, arthritis, jaundice, tetanus, etc.

Ulmi radicis cortex which is used in the present invention refers to thebark of Ulmus davidiana. It is effective against gastric ulcer, duodenalulcer, small bowel ulcer, colon ulcer, edema, dropsy, gastric cancer,rectal cancer, uterine cancer, difficulty urination, ozena, nasitis, aboil, a tumor, a swelling, etc.

Brassica campestris which is used in the present invention refers to arape. The rapeseed contains 38-45% of oil, which is an edible oilcontaining 15-20% of soluble nitrogen compounds and about 20% ofproteins and is consumed in the largest amount next to bean oil. Theresidue remaining after pressing the oil from the seed is used asfeedstuff or manure. The flower is a horny plant, and fatty oilseparated from the seed is used as an ointment base, a solvent for oilyinjection formulations or a lubricant for machines.

Cistanche deserticola stem which is used in the present invention is amedicinal material using the freshy stem of Cistanche deserticola orother similar plants belonging to the family Orobanchaceae. It has apeculiar odor and is sweet, sour, salty and slightly bitter in taste andwarm in nature. It strengthens Yang-Gi and is used for constipationcaused by bowel dryness, lumbago caused by deficiency of the kidneyYang-Qi, a condition in which a leg becomes weak and powerless,tinnitus, forgetfulness, involuntary emission of semen, infertility,leucorrhea, cold abdomen, excessive bleeding, perspiration,constipation, etc. It was reported that the plant has variouspharmacological effects, including lowering blood pressure, promotingsalvia secretion and alleviating respiratory paralysis.

Gypsophila oldhamiana root which is used in the present invention refersto the root of Gypsophila oldhamiana belonging to the familyCaryophyllaceae. It is odorless, acrid in acrid and slightly cold innature. It is used for a fever caused by deficiency of Yin, a fevercaused by overwork, a cold sweat, fever in children and infants,abdominal distension, etc. It was reported that the plant has variouspharmacological effects, including preventing atherosclerosis,preventing cholesterol accumulation and alleviating fever, as well aspermicidal effect.

Eumn-yang-gak which is used in the present invention refers to theabove-ground part of Epimedium koreanum Nakai or other similar plantsbelonging to the family Berberidaceae. It is used for impotence,involuntary emission of semen, cold-uterus conditions, cold-limbconditions, skin paralysis, facial nerve paralysis, forgetfulness,hemiplegia, weak waist and knee, hypertension, infantile paralysis, etc.It was reported that the plant has various pharmacological effects,including promoting semen secretion, lowering blood pressure, increasingcoronary flow, lowering blood glucose levels, lowering blood cholesterollevels, promoting immune functions, relieving asthma and activatingchicken femur growth and proteoglycan synthesis, as well as anantitussive effect, an expectorant effect, a sedative effect, anantibacterial effect, an inflammatory effect.

Coicis semen which is used in the present invention refers to a seedobtained by removing flesh from the seed of Coix lachryma-jobi belongingto the family Gramineae. It is used for dropsy, beriberi, difficulturination caused by a weak stomach, diarrhea, anorexia, limb paralysis,pain, difficult bending and spreading, muscular pain, fever, wounddrainage, typhlitis, etc. It was reported that the plant has variouspharmacological effects, including an anticancer effect, the effect ofinhibiting skeletal muscle contraction, the effect of inhibition thebowel tract and uterine smooth muscle contraction, a sedative effect, ananalgesic effect, an antipyretic effect, etc.

Ik-mo-cho which is used in the present invention refers to a medicinaldrug obtained by drying the above-ground part of Leonurus japonicusHoutt (belonging to the family Lamiaceae) at the time of flowering. Itremoves extravasated blood during amenorrhea, menstrual pain, andbleeding abdominal pain caused by difficult uterine contraction afterchildbirth, and facilitates uterine contraction. It has a light diureticeffect and is used for difficult urination and body swelling, as well aseczema, itching, a boil, etc. It was reported that the plant has variouspharmacological effects, including uterine excitation, thrombolysis,increasing the heart and coronary blood flow, excitation of breathing,urination, suppressing skin fungi, etc.

Alpinia oxyphylla fruit which is used in the present invention is thefruit of Alpinia oxyphylla belonging to the family Zingiberaceae. It isused for abdominal distension caused by a weak stomach, frequenturination caused by weak kidney function, powerless defecation, childrennocturnal enuresis, uterine bleeding during childbirth, and snivelingresulting from deterioration in the convergent function of the spleen.It was reported that the plant has various pharmacological effects,including increasing hart contraction, suppressing ascites tumor cellsand increasing ileum contraction.

Ginseng which is used in the present invention is a perennialdicotyledonous plant belonging to the family Araliaceae of the orderUmbellales. The root is used for medicinal purposes and is human-shaped.Ginseng has been said to be a medicine for eternal youth, Qi enhancementand light body.

In-jin which is used in the present invention refers to a medicinalmaterial obtained by drying the above-ground part of ArtemisiaeCapillaris belonging to the family Compositae. It is used for jaundicecaused by damp heat, and symptoms accompanied by acute hepatitis, thatis, fever, yellowing of the whole body, discharge of red urine, andlittle urination. Also, it is used for chronic hepatitis, cirrhosis,cholecystitis and gallbladder stones. In addition, it is also used forskin diseases, such as eczema, scabies, pityriasis, psoriasis andrubella, as well as high fever and insanity caused by an infectiousdisease. It was reported that In-jin has various pharmacologicaleffects, including promoting bile secretion, alleviating fever,urination, antimicrobial activity, and suppressing ascites tumor cells.

Angelica acutiloba root which is used in the present invention is called“Il-dang-qui”, “Il-bon-dang-qui”, “Oae-dang-qui”, “Cha-dang-qui” or“Gat-gang-hwal” in Korean and grows well in the seashore. The root isused as a medicinal material. It has immune functions, and thus is usedas an anticancer agent and for anemia, menstrual irregularity, menstrualpain, body pain, etc. It is also used as a tonic. It was reported thatthe root has various pharmacological effects, including bloodpressure-lowering and diuretic effects.

Securinega suffruticosa which is used in the present invention has theeffects of activating blood circulation, relaxing muscular tissue,strengthening the spleen and improving kidney functions. It is used totreat rheumatoid lumbago, limb paralysis, hemiplegia, impotence, facialnever paralysis, residual poliomyelitis, etc.

Cnidium officinale which is used in the present invention is a perennialplant belonging to the family Umbelliferae and is called“Il-cheon-goong”, “Cheon-goong”, “Goong-goong yi” or “Oae-cheon-goong”in Korean. It is effective in alleviating pain, suppressing convulsions,eliminating paralysis and promoting blood circulation.

Aster root which is used in the present invention refers to the root ofAster tataricus belonging to the family Compositae. It has a peculiarodor and is acrid and slightly bitter in taste and warm in nature. Itacts to strengthen lung function, and thus is used for cough, phlegm,asthma and to enhance Qi and relive asthma. Particularly, it is used totreat an old cough and bloody phlegm. In addition, it is also used for asour throat and acute and chronic respiratory infections. It wasreported that the root has various pharmacological effects, includingantitussive, expectorant and antimicrobial effects, as well as theeffect of suppressing ascites tumor cells.

Lithospermum erythrorhizon which is used in the present invention is amushroom growing on tree branches rising above the water in lakes,ponds, swamps and the like.

Paeonia which is used in the present invention refers to a collection ofperennial plants belonging to the family Ranunculaceae. It is cultivatedfor ornamental purposes in a garden, because the flowers are large andbeautiful. Examples thereof include Paeonia alviflora, Paeonia japonica,Paeonia obovata, Paeonia albiflora and the like. It is bitter and sourin taste and slightly cold in cold. It acts to clarify blood andeliminate extravasated blood, and thus is used for fever, hemoptysis,amenorrhoea, a bruise and the like.

Adenophora triphylla which is used in the present invention is aperennial plant belonging to the family Campanulaceae of the orderCampanulales and is called “Jan-dae”, “Sa-sam”, “Dak-ju” or Je-ni” inKorean. The root of the plant is used as antitussive, expectorant,antipyretic, tonic and pus-draining agents.

Ailanthus altissima bark which is used in the present invention refersto the root bark of Ailanthus altissima. In Chinese medicine, it iseffective against leucorrhea, diarrhea and bloody feces.

Grifola umbellata which is used inn the present invention is a mushroombelonging to the family Polyporaceae of the order Aphyllophorales of theclass Basidiomycetes. In Chinese medicine, it is used as a diureticagent.

Poria cocos red which is used in the present invention is the sclerotiumof Poria cocos (Polyporaceae) which is parasitic on the pine root. Itrefers to a medicinal material obtained by removing the outer layer ofthe sclerotium. It is obtained by removing the outer layer with a knife,cutting the remaining inner part to a suitable size and drying the cutmaterial in sunlight. Herein, when the inner part is white, it isreferred to as Poria cocos white, and when the inner part is red, it isreferred to as Poria cocos red. Poria cocos is used for difficulturination, abdominal and systemic edema, a cough by phlegm, vomiting,diarrhea, forgetfulness by hypersensitivity, involuntary emission ofsemen, and cardiac edema. It was reported that the medicinal materialhas various pharmacological effects, including urination, an antifungaleffect, relaxation of gastrointestinal tract muscle, ulcer prevention,lowering blood glucose levels, increasing heart contraction, boostingimmunity, an antitumor effect, etc.

Polygonum multiflorum root which is used in the present invention refersto a medicinal material obtained by drying the root of Polygonummultiflorum Thunberg. It is obtained by collecting the root of Polygonummultiflorum Thunberg in the fall and cutting or splitting the collectedroot, followed by drying. It is used to protect the bowels and stopdiarrhea.

Red cabbage which is used in the present invention is a kind of cabbagebelonging to the family Cruciferae. It is a health food which iseffective in preventing gastric ulcer and aging and in restoring liverfunction. It is frequently used for decorative purposes in salad becauseof its beautiful color and is also used as sprout vegetables. It isricher in nutrients, such as fructose, glucose, vegetable proteinlysine, and vitamin C, than common white cabbage. Also, it is rich invitamin U, and thus effective against gastric ulcer. In addition, it isalso rich in selenium which functions to prevent aging and mercurypoisoning and restore liver function. However, it must be avoided that aperson having low body temperature and suffering from frequent diarrheatakes red cabbage in a large amount.

Paeoniae Radix Rubra which is used in the present invention is a kind ofPaeoniae Radix, and when the root is cut, it is reddish.

Anthriscus sylvestris which is used in the present invention isperennial plant belonging to the family Umbelliferae. It grows to aheight of about 1 m, and the branch is split. The leaves have longstalks and are divided into feather shapes. In Chinese medicine, itrefers to the root of Angelica decursiva and is used for headache,cough, phlegm, etc.

Sorbus commixta cortex which is used in the present invention refers tothe stem cortex of Sorbus commixta which is a deciduous dicotyledonoustree belonging to the family Rosaceae of the order Rosales ofArchichlamydeae. It has tonic, paralysis-removing and antitussiveeffects and is used to treat body weakness, sore waist and knee, limbparalysis by rheumatism, cough, white hair, etc.

Syzygium aromaticum which is used in the present invention refers to aclove bud. It is known that the plant is sweet and hot in taste, andthus effective in promoting appetite.

Gleditsiae fructus which is used in the present invention is also called“Jo-gak” or Jo-hyup” in Korean and refers to the fruit of Gleditsiajaponica belonging to the family Leguminosae. It has a strongexpectorant effect and is used for tuberculosis, lung abscess, chronicbronchitis, etc. It is also used for mental numbness by paralysis,unconsciousness, epilepsy, a boil, skin ulcer, constipation, etc. It wasreported that the medicinal material has various pharmacologicaleffects, including stimulating gastric mucosa, promoting mucoussecretion in respiratory tracts, antibacterial activity, suppressingcentral nervous paralysis, etc.

Gleditsiae spina which is used in the present invention refers to thethorn of Gleditsia japonica belonging to the family Leguminosae. It hasstrong diuretic and anti-inflammatory effects, and thus is used to treatboils and neutralize boil's poison. It was reported that the medicinalmaterial alleviates fever in acute tonsillitis and has ananti-inflammatory effect.

Lophatherum gracile which is used in the present invention refers to amonocotyledon bamboo belonging to the family Gramineae of the orderGraminales.

Cistanche deserticola stem which is used in the present invention isalso called “Yuk-jong-yong” and is a medicinal material using the freshystem of Cistanche deserticola or other similar plants belonging to thefamily Orobanchaceae. It strengthens Yang-Gi and is used forconstipation caused by bowel dryness, lumbago caused by deficiency ofthe kidney Yang-Qi, a condition in which a leg becomes weak andpowerless, tinnitus, forgetfulness, involuntary emission of semen,infertility, leucorrhea, cold abdomen, excessive bleeding, perspiration,constipation, etc. It was reported that the plant has variouspharmacological effects, including lowering blood pressure, promotingsalvia secretion and alleviating respiratory paralysis.

Phyllostachys nigra sheath which is used in the present invention refersto the inner sheath of Bambusa textilis and has the effects of loweringfever, stopping vomiting, alleviating phlegm and stabilizing a fetus.

Lycium chinensis root which is used in the present invention refers tothe dried root bark of Lycium chinensis. It is used for a cold sweatcaused by body weakness, a cough, asthma, hemoptysis, nasal bleeding,bloody urine, hyperglycemia, high fever, neuralgia, headache, shoulderpain, muscular pain, lumbago, weak waist and knee, etc. It was reportedthat the root has various pharmacological effects, including loweringblood pressure and blood glucose levels.

Hovenia dulcis bark which is used in the present invention refers to thestem bark of Hovenia dulcis. It acts to facilitate blood circulation andrelax muscle. It was reported to have the pharmacological effect ofprotecting the liver.

Anemarrhena asphodeloides which is used in the present invention is amonocotyledonous plant belonging to the family Haemodraceae of the orderVeneroida, and the rhizome thereof contains asphonin, sarsapogenin,etc., which can be used as medicinal components. In Chinese medicine,the rhizome is used as a medicinal material, and it is used as anantipyretic agent and was reported to be effective against chronicbronchitis, diabetes and the like.

Kochiae fructus which is used in the present invention is also“Ji-bu-ja”, “Dae-ssa-ri” or “Bi-ssa-ri” in Korean and refers to the seedof an annual plant belonging to the family Chenopodiaceae. It is used asa tonic and a diuretic and was reported to be effective againsthyperthyroidism and atopic symptoms.

Poncirus trifoliate fruit which is used in the present invention refersto the young fruit of Poncirus trifoliate. It was found to be effectiveagainst a condition in which the chest and abdomen feel filling andswelling due to Qi stagnation, a condition the chest feels heavy andfeels pain when being pressed, as well as edema, indigestion,constipation, etc. It was recently found that the fruit is effectiveagainst gastroptosis, uterine prolapse, protocele, etc. It was reportedthat the fruit has various pharmacological effects, including uterinecontraction, gastric movement acceleration, heart stimulation,urination, etc.

Sanguisorba officinalis which is used in the present invention is usedfor diarrhea, colitis, bleeding, malignant boils, burns, etc.Particularly, it has strong hemostatic activity, and thus is used tostop bleeding.

Rehmannia radix which is used in the present invention is a plantbelonging to the family Scrophulariaceae. It is classified into rawRehmannia glutinosa which is the raw root of the plant, dried Rehmanniaglutinosa which is obtained by drying the root, and Rehmanniae radixpreparata which is obtained by steaming and drying the root. Rehmanniaeradix preparata is used as a hematic and for menstrual irregularity, aweak constitution, children physical retardation, dementia, prematureejaculation, impotence and the like. Raw Rehmanniae radix is used for aweak constitution, hemoptysis, nasal bleeding, uterine bleeding,constipation and the like, and dried Rehmanniae radix is effectiveagainst thirst occurring after fever disease, and a disease symptomizedby thirst due to the heat of the bowels, and acts to stop hemoptysis andnasal bleeding.

Aconitum pseudolaeve Nakai which is used in the present invention is aplant belonging to the family Ranunculaceae. In Chinese medicine, thedried root of the plant is used as a medicinal material, and it wasreported to have paralysis-removing, analgesic and diuretic effects, andthus is used for arthritis, convulsions of muscle and bone, jaundice,difficult urination, etc.

Jin-o-ga-pi which is used in the present invention refers to a kind ofAcanthopanax. It acts to eliminate wind-damp, promote blood circulationand relieve pain and functions to enhance kidney function to strengthenmuscle and bone.

Phyllanthus urinaria which is used in the present invention is an annualplant of the family Euphorbiaceae, which grows in fields or grassfields. It is also called “Jin-ju-cho”, “Yeo-woo-gu-seul”,“Il-gae-ya-pye”, “Sip-ja-jin-ju-cho”, “Um-yang-cho”, “Ga-yu-gam”,“Jeuk-eo-cho”, “Ho-su-su”, “No-a-ju”, “Ya-hap-jin-ju”, “Rak-ji-yu-gam”,“So-ri-gam”, “Hal-cho”, “Ya-hap-cho”,“San-jo-gak”, “Yup-hu-ju”,Yu-gam-cho” or “Eo-rin-cho” in Korean. It is known to be effectiveagainst chronic hepatitis, nephritis, enteritis and dysentery and hasthe effect of improving eyesight.

Citrus unshiu peel which is used in the present invention refers to thefruit peel of Citrus unshiu. It acts to relax Qi and enhance thefunction of fat, and thus is used to treat abdominal distension,belching, vomiting, nauseating, indigestion, flatulence and languishing,and loose feces. It relives cough and phlegm and facilitates urination.It was reported that the essential oil components of the peel hasvarious pharmacological effects, including stimulating the digestiveorgans, promoting digestion, loosening phlegm, antiulcer activity,inhibiting gastric juice secretion, stimulating the heart, elevatingblood pressure, antiallergic activity, promoting bile secretion,inhibiting uterine smooth muscle contraction, antimicrobial activity,etc.

Plantaginis semen which is used in the present invention refers to theseed of Plantago asiatica. It is used to facilitate urination, alleviatediarrhea, improve eyesight and stop coughing.

Xanthium strumarium fruit which is used in the present invention refersto the fruit of Xanthium strumarium belonging to the family Compositae.It is a medicinal material for eliminating “wind-cold” and is used forozena, nasitis, headache, pyrexia, coughing, limb paralysis, difficultbending and spreading, itching, otitis media and the like. It wasreported that the fruit has various pharmacological effects, including atoxic response to essential oil and alkaloid, lowering blood glucoselevels, preventing the reduction of leucocytes, antitussive activity,promoting cardiovascular exercise, etc.

Cnidii rhizoma which is used in the present invention is a plantbelonging to the family Umbelliferae. In Chinese medicine, the rhizomeof the plant is used for headache, anemia, women's diseases and thelike, because it has sedative, analgesic and tonic effects.

Gastrodia elata which is used in the present invention refers to aperennial monocotyledonous plant belonging to the family Orchidaceae ofthe order Orchidales. The whole plant is used as a tonic and for nervousbreakdown, dizziness, headache, etc.

Asparagus cochinchinensis which is used in the present invention is aplant belonging to the family Veneridae. The soft shoot of the plant isused for eating purposes, and the root is used as antitussive, diureticand tonic agents. It was reported that the plant must not be used for aperson whose body is cold and who has a bowel trouble and thus suffersfrom diarrhea.

Zanthoxyli frustus which is used in the present invention is called“Cheon-cho” or “San-cho” and is the fruit peel of Zanthoxylum piperitumbelonging to the family Rutaceae, which is obtained by removing a seedfrom the fruit. It is used for an abdominal pain caused by the chill ofthe abdomen, diarrhea, toothache, lumbago, etc. Also, it hasinsecticidal activity, and thus is used for scabies, scabs, itching ofthe secret parts, scrotal eczema, etc. It was reported that the fruitfeel has various pharmacological effects, including regional anesthesia,gastrointestinal tract peristalsis, antibacterial activity, etc.

Semiaquilegia adoxoides which is used in the present invention is called“frog claw” in Korea and grows to a height of 20-30 cm in the mountainbase. In Chinese medicine, it is used for difficult urination, urinarystones, inflammation of the lymphatic gland, piles, uteritis, gonorrhea,epilepsy and the like. In fork remedies, it is pulverized and applied tosnake or insect bites.

Opuntia humifusa which is used in the present invention is also calleddracaena, and about 50 kinds of dracaena are distributed in the tropics.The leaves are parallel veined, leathery, and lanceolate or broad-ovate.The leaves are 30-50 cm in length and 6-10 cm in width and have stalks.The stem is woody and upright, and spikelets are attached to the end ofthe stem. Small flowers, each having 6 flower leaves, grow in clusters.

Dioscorea nipponica Makino which is used in the present invention isalso called “Cheon-san-ryoung” or “Dan-pung-ma” in Korean. In Chinesemedicine, the rhizome of the plant is immersed in an alcoholic beverageand used for a condition resulting from the clotting and coagulation ofextravasated blood. Also, it is used for coronary artery disorderscaused by extravasated blood, acts to alleviate the coughing and asthmacaused by the lung fever and to lower the blood fever, and thus is usedfor boils and rashes on the skin.

Saussurea involucrata which is used in the present invention is aperennial plant of the family Ranunculoideae, which grows in Tian ShanMountain in China. In the plant, fibrous roots spread out from a thickand short rhizome in clusters, the stem is upright, and the base of thestem is surrounded by scaly leaves. It is known that the plant aids therejuvenation of the male and is highly effective against women'sdiseases, cold-related diseases, kidney disease, arthritis, diabetes,wind-damp, uterine coldness, sickliness, etc.

Trichosanthes kirilowii root which is used in the present invention iscalled “Cheon-wha-boon” or “Kual-ru-keun” in Korean and refers to theroot of Trichosanthes kirilowii Maximowicz or Trichosanthes kirilowiiMax. var. japonica Kitamura of the family Cucurbitaceae, from which thecortex has been removed. It is used to treat a disease symptomized bythirst, which occurs when body fluid is deficient due to fever, as wellas boils and pus. It acts to bring down the fever of mainly the lungsand the stomach and to make body fluid so as to relieve thirst andcomfort the body. It was reported that the plant has variouspharmacological effects, including suppressing squamous cell carcinoma,stimulating uterine smooth muscle contraction, inhibiting liver cells,lowering blood glucose levels, and inhibiting bacteria.

Artemisia apiaceae Herba which is used in the present invention iscalled “Cheong-Ho” in Korean. It acts to reduce hemorrhagic fever totreat malaria and the nausea, headache and vomiting caused by hotweather. Also, it is used to treat bone pain caused by consumptivefever, symptoms involving a slight fever, and a summer cold. Inaddition, it acts to improve the face color and make white hair black.It was reported that the plant has various pharmacological effects,including inhibiting malarial parasites and distoma hepaticum, loweringblood pressure, alleviating fever and inhibiting dermatomycosis, as wellas antitussive, expectorant, asthma-relieving, bile-secreting andimmunity-regulating effects.

Amomi tsao-ko fructus which is used in the present invention refers tothe fruit of Amomum tsao-ko CREVOST belonging to the familyZingiberaceae. It acts to warm the stomach and spleen and remove dampand is used for abdominal pain, abdominal distension, nausea, vomiting,diarrhea, etc.

Aconiti ciliare tuber which is used in the present invention refers tothe tuber root of Aconitum cliliare or other plants belonging to thefamily Ranunculaceae. It is used for headache, abdominal pain, boils,hemiplegia, unconsciousness and Bell's palsy. Also, it is used to treatthe paralysis or unconsciousness caused by wind-damp disease, rheumatoidarthritis, neuralgia, lumbago, tetanus, an abdominal pain caused byabdominal coldness, etc. It was reported that the plant has variouspharmacological effects, including analgesic, sedative,anti-inflammatory and partial paralysis-relieving effects and stimulatesthe heart work, when it is administered in a large amount.

Gardeniae fructus which is used in the present invention refers to thefruit of Gardenia jasminoides which is an evergreen shrub belonging tothe family Rubiaceae. In Chinese medicine, it is used to treat insomniaand jaundice and has anti-inflammatory, hemostatic and diuretic effects.

Celosiae semen which is used in the present invention refers to the seedof Celosia argentea Linne belonging to the family Amaranthaceae. Itbrings down liver fever, and thus is used for congestion, white coating,hypertension, headache, etc. It is pharmacologically used for ophthalmicdiseases and skin boils.

Althaea rosea which is used in the present invention refers to ahollyhock belonging to the family Malvaceae. It is used for leucorrhea,abdominal coldness, difficult urination and defecation, uterinebleeding, redness of the nasal tip, etc. It was reported to have apharmacological effect against malaria.

Aquillaria agallocha which is used in the present invention is anevergreen tree belonging to the family Thymelaeaceae. In Chinesemedicine, the stem is medicinally used and has sedative, stomachic andQi-circulating effects. In addition, it is effective againstindigestion, inappetence, vomiting, bronchial asthma, prematureejaculation, a decline in energy, etc.

Taek-ran which is used in the present invention refers to theabove-ground part of Lycopus lucidus belonging to the family Labiataebefore the time of flowering. It is used for amenorrhoea caused byextravasated blood, menstrual pain, abdominal pain after childbirth, anda bruise, and is effective against boils, liver function disturbance,and difficult urination after childbirth. It has an advantage in that itexpels extravasated blood without damaging sprit and energy, and thus itis frequently used in gynecology. It was reported to have a cardiotoniceffect.

Alisma canaliculatum which is used in the present invention is “Taek-sa”or “Swe-tae-na-mul” in Korean. In Chinese medicine, the rhizome is usedas a diuretic agent and for dropsy and gonorrhea.

Ponciri fructus which is used in the present invention is the fruit ofPoncirus trifoliate. It smells good and is also used for medicinalpurposes.

Smilacis chinae radix which is used in the present invention refers tothe root of Smilax china Linne. It contains a large amount of starch andis known to be effective against constipation, syphilis, gonorrhea,infant eczema, malignant boils, chronic dermatitis, mercury poisoning,flu, neuralgia, etc.

Cuscutae semen which is used in the present invention refers to the seedof Cuscuta japonica which is an annual climbing plant belonging to the,family Convolvulaceae. It is known as a medicinal material whichprotects the liver and kidneys, improves eyesight, promotes Yang-qi andstrengthens the kidneys. It is effective against male impotence causedby kidney weakness, spontaneous semen emission, a wet dream, etc. Itacts to strengthen bone and the waist, and the sourness and pain of thewaist and knee caused by weak kidney function. Also, it was reportedthat the plant is effective in treating diseases, involving urinaryincontinence and difficult urination, and diabetes.

Ligusticum rhizome which is used in the present invention is the root ofLigusticum chuanxiong. It has antispasmodic, sedative, blood pressurelowering, vasodilator and antibacterial effects.

Tetrapanacis medulla which is used in the present invention refers tothe stem of Tetrapanax papyriferus belonging to the family Araliaceae.It is known to bring down fever and increase urination. Thus, it is usedto treat gonorrhea, urethritis and cystitis and promotes milk secretionafter childbirth.

Morinda offcinalis How which is used in the present invention is called“Pa-keuk-cheon” or “No-ni” in Korean. In folk remedies, the leaf, stem,flower, fruit and seed of the plant have been used. In the ancientliterature known in the South Pacific area, the plant is recorded as thebest natural therapeutic agent. It was, in fact, found that the plantcontains anthraquinone, serotonin and the like, and thus promotesdigestion, alleviates pain and is effective against hypertension andcancer. It grows mainly in volcanic soil while taking root deep.

Tiglii semen which is used in the present invention refers to the seedof Croton tiglium which is an evergreen broad-leaved shrub belonging tothe family Euphorbiaceae. It is hot in taste and poisonous and is usedfor constipation or a condition in which the abdomen feels bloated dueto filling of the abdomen with fluids.

Taraxaci Herba which is used in the present invention refers to thedried whole plant of Taraxacum platycarpum or other plants belonging tothe same family. It acts to alleviate fever-poison and resolve boils andis used for boils, mastitis, a sore throat, carbuncles (appendicitis,Lung abscesses, and peritonitis), eyeball congestion, acute hepatitis,jaundice, difficult urination caused by fever, etc. It was reported thatthe plant has various pharmacological effects, including antibacterial,immune function-enhancing, bile-secreting, liver function-protecting anddiuretic effects.

Typhae pollen which is used in the present invention refers to thepollen of Typha orientalis or other plants belonging to the familyTyphaceae. It acts to bring down hemorrhagic fever and has convergentand hemostatic effects. It is used for hemoptysis, nasal bleeding anduterine bleeding. Also, it acts to improve blood circulation, and thusis used for the heart and abdominal pain caused by blood aggregation inthe chest, a pain caused by extravasated blood after childbirth, andmenstrual pain. It was reported that the plant has variouspharmacological effects, including stimulating uterine contraction,lowering blood pressure, antimuscarinic activity, shortening the bloodcoagulation time, inhibiting the growth of tubercle bacilli, andlowering cholesterol levels.

Calypso bulbosa which is used in the present invention is called“Pung-seon-nan-cho”, “Pung-seon-ran” or “Po-dae-ran” in Korean. It growsin coniferous forests to a height of about 30 cm. The rhizome is fleshyand ovate, and one leaf and stem come out from the tip of the rhizome.The leaf has a stalk and is egg-shaped or ovate. Also, the leaf is sharpat the end, round at the base, wrinkled vertically, and purple at thebackside.

Polygonum multiflorum tuber which is used in the present invention isnative to China and cultivated for medicinal purposes. It is reddishbrown in color and used as a tonic, an aphrodisiac and a palliative. Theleaf of the plant is used as seasoned vegetables, and the raw leaf isapplied to a boil so as to absorb the pus.

Aeschynomene indica which is used in the present invention is called“Hap-maeng” or “Ja-gui-pul” in Korean. It grows in swampy land, and thestem is upright and grows to a height of 50-80 cm. The stem is branchedand hollow at the top. The leaves are alternate and pinnately compoundleaves. The leaflets consist of 20-30 pairs are ovate, plain at themargin and whitish at the backside.

Armeniacae semen which is used in the present invention refers to anapricot seed and is used for coughing, asthma, constipation and thelike.

Helianthus annus seed which is used in the present invention refers tothe seed of sunflower and acts to lower cholesterol levels and preventcardiovascular diseases and arteriosclerosis. Also, it is rich inminerals, such as calcium, potassium and iron, and is highly effectivefor people whose respiratory organs are weak and body is cold and weak.In addition, it is rich in vitamin B antibody, and thus highly effectiveagainst hypertension or hypersensitivity.

Cyperus rotundus which is used in the present invention is a perennialplant belonging to the family Cyperaceae. The tuber root of the plantcontains essential oil and fatty oil, and in Chinese medicine, it isused for headache, abdominal pain and menstrual irregularity. In folkremedies, it is also used as an antitussive in tuberculosis.

Elsholtzia ciliata which is used in the present invention is a plantbelonging to the family Labia tae and is called “Hyang-yu” or “No-ya-gi”in Korean. In Chinese medicine, a medicinal material obtained by dryingthe whole plant at the time of flowering is used as diaphoretic,antipyretic, diuretic and hemostatic agents and for boils, beriberi,dropsy, gastritis, nasitis and bad breath.

Cedrela sinensis fruit which is used in the present invention refers tothe fruit of Cedrela sinensis. It has the effects of removing paralysis,dispersing cold and relieving pain and is used to treat a disease causedby exogenous wind-cold, a heart or stomach pain, rheumatoid arthritis,and abdominal and waist pains.

Typha orientalis pollen which is used in the present invention is called“Hyang-po” or “Po-hwang” in Korean and refers to the pollen of Typhaorientalis or other plants belonging to the family Typhaceae. It acts tobring down hemorrhagic fever and has convergent and hemostatic effects.It is used for hemoptysis, nasal bleeding and uterine bleeding. Also, itacts to improve blood circulation, and thus is used for the heart andabdominal pain caused by blood aggregation in the chest, a pain causedby extravasated blood after childbirth, and menstrual pain. It wasreported that the plant has various pharmacological effects, includingstimulating uterine contraction, lowering blood pressure, antimuscarinicactivity, shortening the blood coagulation time, inhibiting the growthof tubercle bacilli, and lowering cholesterol levels.

Scrophulariae radix which is used in the present invention is aperennial plant belonging to the family Scrophulariaceae and is called“Hyun-sam”, “Joong-dae”, “Hyun-dae”, “Gui-jang” or “Chook-ma” in Korean.In Chinese medicine, the root is used as an antipyretic and for a sorethroat, boils, inflammation of the lymphatic gland, etc.

Geranium nepalense which is used in the present invention is an annualplant belonging to the family Geraniaceae. It acts to remove wind-dampand promote blood circulation to strengthen bone and muscle, and thus isused for paralytic pain, joint discomfort, a bruise, etc. In addition,it is effective against dysentery, chronic diarrhea and abdominal pain,enteritis, itching, scabies, malignant boils, etc.

Corydalis turtschaminovii which is used in the present invention is aperennial plant belonging to the family Fumariaceae of the orderPapaverales and is “Hyun-ho-sac”, “Nam-wha-chae” or “Won-ho” in Korean.In Chinese medicine, the tuber is used as a hematocathartic, anantispasmodic and an analgesic.

Schizonepeta tenuifolia which is used in the present invention is anannual plant belonging to the family Lamiaceae. In Chinese medicine, thedried whole plant is used for headache, a sore throat, and the casewhere boil sites bleed.

Sesamum indicum which is used in the present invention refers to sesameor black sesame. It acts to protect the liver and kidneys and iseffective for people who have boils or a lot of gray hair.

Trigonella foenum-graecum which is used in the present invention is anannual plant belonging to the family Leguminosae of the order Rosalesand grows to a height of about 50 cm. The Trigonella seed is medicinallyused, after it is generally dried in sunlight. The seed contains a verysmall amount of essential oil which contains about 40 components,including alkaloids, proteins, fats, etc. It is warm in nature andnon-poisonous, and thus has been used to treat diseases of the bladderand kidneys in Africa, the Middle East, India and others. It has alsobeen used to treat a cold sweat or abdominal distension. These days, itis being actively studied, because it is effective in maintaining thebalance between glucose and insulin in the body and regulatingbodyweight.

Cucurbita spp which is used in the present invention is an annualclimbing plant belonging to the Cucurbitaceae. It is known that theplant has the highest starch content among fruits and vegetables and thecalorie value thereof is ranked next to potatoes, sweet potatoes andbeans. It is generally used for cooking, and the ripened pumpkin is veryimportant as a vitamin source, because it contains a large amount ofvitamin A and some amounts of vitamins B and C.

Acanthopanax giraldii which is used in the present invention refers toAcanthopanax senticosus whose thorn is purplish red in color.

Red ginseng which is used in the present invention is obtained bysteaming and drying fresh ginseng. It performs sedative action andstimulant action in the central nerve and acts on the circulating systemto prevent hypertension or arteriosclerosis. Also, it has ahematopoietic effect, lowers blood glucose levels, protects the liver,acts on the endocrine system to act indirectly on sexual behavior orgenerative function, has anti-inflammatory and anti-tumor effects and adefense effect against radiation, and protects and smoothes the skin.One important effect of red ginseng is an adaptogen effect, and it hasbeen scientifically proved that red ginseng has the ability to increasethe defense ability of the living body against various harmful effects(stress, etc.) from the surrounding environment so as to allow theliving body to more easily adapt to the environment.

Kombucha which is used in the present invention is a tea containingsugar, is prepared by culturing yeast and has an acid taste similar tothat of lemon tea. Most of the acid taste is acetic acid, and Kombuchaalso contains organic acids such as gluconic acid.

Herba Trifolii pratensis which is used in the present invention is aperennial plant belonging to the family Leguminosae and is called“Hong-cha-chook-cho”, “red clover” or “Keum-wha-chae” in Korean. In folkremedies, the whole plant is used as diuretic, analgesic, digestant,stomachic, expectorant and hemostatic agents, etc.

Carthamus tinctorius which is used in the present invention is the driedflower of Carthamus tinctorius. In Chinese medicine, it is used forwomen's diseases, menorrhalgia and abdominal pain, and the seed oil isused as lamp-oil and for eating purposes. The seed oil is rich inlinolic acid, and thus effective in preventing and treatingarteriosclerosis caused by hypercholesterolemia.

The floral envelop which is used in the present invention is a floralelement which is located outside a stamen and a pistil so as to protectthe stamen and the pistil.

Scutellaria baicalensis Georgi which is used in the present invention isa perennial plant belonging to the family Lamiaceae. In Chinesemedicine, the root of the plant is used as antipyretic, diuretic,antidiarrheal, expectorant and anti-inflammatory agents.

Astragalus membranaceus which is used in the present invention refers toa perennial plant belonging to the family Leguminosae. It is frequentlycultivated as an herb, and in Chinese medicine, it is obtained bycollecting the plant in the fall, removing the head and root hairs fromthe collected plant and drying the residue in sunlight. It has tonic,antiperspirant, diuretic and anti-tumor effects, and thus is used forbody weakness, fatigue, languor, deficiency of Qi blood, proctocele,uterine prolapse, a cold sweat, a peripheral nerve, etc.

Coptis chinensis Franch which is used in the present invention iscultivated for medicinal purposes. In Chinese medicine, it is obtainedby collecting the root of a 5-6-old-year plant in November and dryingthe collected root in sunlight. It has stomachic, sedative,anti-inflammatory and antibacterial effects, and thus is used to treatindigestion, gastritis, enteritis, abdominal pain, vomiting, dysentery,heart palpitation, a febrile disease, mental anxiety, throat pain,hemoptysis, nasal bleeding, blood discharging, burns, etc.

Polygonatum lasianthum radix which is used in the present invention theroot of Polygonatum lasianthum. It is used for body weakness,languidness, and weight loss.

Lindera obtusiloba branch which is used in the present invention refersto the dried branch of Lindera obtusiloba. In Chinese medicine, it isused for extravasated blood, after-pain, abdominal pain, and phlegm.

Phellodendron amurense bark which is used in the present inventionrefers to the dried bark of Phellodendron amurense belonging to thefamily Rutaceae and is “Hyang-baek” or “Hyang-kyung-pi” in Korean. It isobtained by collecting the bark from the tree stem, removing a coarsebark from the collected bark or cutting the bark, and drying theresulting bark in sunlight. The bark is medicinally used, acts to lowerblood glucose levels, inhibit the growth of Pneumococcus, mycobacteriumtuberculosis, Staphylococcus and the like and suppress the growth oftumor cells, and has a bactericidal effect. When it is administered, itstimulates the secretion of gastric juice by the acceleration of tastereflex and promotes appetite. Because it has no systemic action, unlikegeneral alkaloids, it has no side effects, even when it is administeredin a large amount. Thus, it can be used as intestinal antiseptic andstomachic agents. Also, because various kinds of bacteria do nottolerate the medicinal material, it can be used as an eye washing andsterilizing drug. In addition, it was reported to have the effects oflowering blood pressure, suppressing the central nervous system andinhibiting inflammation, and thus Hwang-ryun-hae-dok-tang,Si-ho-cheong-gan-tang, Hyeong-gae-yeon-gyo-tang and the like in Chinesemedicine.

Magnolia obovata which is used in the present invention is an evergreendicotyledonous tree belonging to the family Lauraceae of the orderRanales. In Chinese medicine, the bark of the tree is used for asthmaand stomach trouble.

Black Pharbitis semen which is used in the present invention refers tothe black seed of Pharbitis nil Choisy. It is obtained by collecting theseeds between September and October, drying the collected seeds,selecting only seeds having a dried fresh from the dried seeds, anddrying the dried seeds. The dried seeds are classified into whitePharbitis semen having a white outer surface and black Pharbitis semenhaving a red outer surface. White Pharbitis semen and black Pharbitissemen have the same medicinal effects.

Siegesbeckiae Herba which is used in the present invention refers to theabove-ground part of Siegesbeckia glabrescens Makino or Siegesbeckiapubescens Makino belonging to the family Compositae. It acts to removewind-damp and is used for arthritis, limb pain and paralysis, difficultbending and spreading, lower-limb languidness, and hemiplegia. Inaddition, it is also used for boils, rashes, itching, eczema,hypertension, headache, dizziness, acute hepatitis, etc. It was reportedto have various pharmacological effects, including inhibiting jointedema and lowering blood pressure.

The method for extracting medicinal plants, which is used in the presentinvention, is as follows.

(1) Step of Processing Medicinal Plants

Medicinal plants are processed by boiling or steaming, roasting, bakingor heating them.

Specifically, processing is carried out at 60-100□ for 2-10 hours forboiling, 100-150□ for 30 minutes to 12 hours for steaming, 100-180□ for10 minutes to 5 hours for roasting, and 150-300□ for 5-24 hours forbaking.

If the processing conditions are out of the above-specified ranges, itwill be difficult to obtain the desired effects, or the degree ofimprovement in effects will be insufficient.

(2) Step of Obtaining Extracts

Extracts of the medicinal plants processed in step (1) are obtainedusing water or an organic solvent. The organic solvent may be at leastone selected from the group consisting of ethanol, methanol, butanol,ether, ethyl acetate and chloroform. Alternatively, a mixed solvent ofthe organic solvent with water may also be used. Preferably, 80% ethanolmay be used.

The cosmetic composition of the present invention contains, as an activeingredient, the medicinal plant extract prepared as described above, inan amount of 0.001-30 wt % based on the total weight of the composition.If the content of the extract is less than 0.001 wt %, it will bedifficult to obtain the desired effects, and if the content is more than30 wt %, the change in effects will be insufficient.

Advantageous Effects

The inventive composition for skin external application, which containsan extract of a processed medicinal plant, shows an excellentantioxidant effect by inhibiting DPPH oxidation. Thus, the extract canbe contained in a cosmetic composition or a pharmaceutical compositionso as to provide an excellent antioxidant effect.

BEST MODE

Hereinafter, the present invention will be described in further detailwith reference to examples and test examples. It is to be understood,however, that these examples are for illustrative purposes and are notto be construed to limit the scope of the present invention.

Comparative Example 1 Preparation of Unprocessed Terminalia chebula RetzFlesh Product

1 kg of dried Terminalia chebula Retz flesh was added to 5 L of 80%ethanol aqueous solution, extracted three times under reflux, and thenmaintained at 15□ for 1 day. Following this, the solution was filteredthrough filter cloth and centrifuged into the residue and a filtrate.The separated filtrate was concentrated under reduced pressure, thusobtaining a Terminalia chebula Retz flesh extract.

Example 1-1 Preparation of Salted Terminalia chebula Retz Flesh

1 kg of dried Terminalia chebula Retz flesh was mixed well with brine(2-3% salt), closed and allowed to stand such that the brine wascompletely absorbed into the plant. Then, the plant was placed in avessel at 100-180□ and roasted for 10 minutes to 1 hour, followed bydrying in the shade. The dried material was added to 5 L of 80% ethanolaqueous solution, extracted three times under reflux, and thenmaintained at 15□ for 1 day. Then, the solution was filtered throughfilter cloth and centrifuged into the residue and a filtrate, and theseparated filtrate was concentrated under reduced pressure, thusobtaining an extract of salted Terminalia chebula Retz flesh.

Example 1-2 Carbonized Terminalia chebula Retz Flesh

The surface of 1 kg of dried Terminalia chebula Retz flesh wascarbonized by heating at 230-300□, and when the surface was turnedblack, the heating was stopped and the plant was cooled at roomtemperature. Then, the carbonized plant was added to 5 L of 80% ethanolaqueous solution, extracted three times under reflux, and thenmaintained at 15□ for 1 day. Then, the solution was filtered throughfilter cloth and centrifuged into the residue and a filtrate, and theseparated filtrate was concentrated under reduced pressure, thusobtaining an extract of carbonized Terminalia chebula Retz flesh.

Example 1-3 Preparation of Vinegared Terminalia chebula Retz Flesh

1 kg of dried Terminalia chebula Retz flesh was sufficiently absorbedwith 200-300 g of vinegar, and was then roasted at 100-160□ for 10minutes to 1 hour and dried in the shade. The dried plant was added to 5L of 80% ethanol aqueous solution, extracted three times under reflux,and then maintained at 15□ for 1 day. The, the solution was filteredthrough filter cloth and centrifuged into the residue and a filtrate,and the separated filtrate was concentrated under reduced pressure, thusobtaining an extract of vinegared Terminalia chebula Retz flesh.

Example 1-4 Preparation of Alcohol Steamed Terminalia chebula Retz Flesh

1 kg of dried Terminalia chebula Retz flesh was immersed in a givenamount of huang-chiew (brewed alcoholic beverage), such that it was wet.The wet plant was steamed in a steamer for 30 minutes to 2 hours, andthen dried in the shade. The steamed plant was added to 5 L of 80%ethanol aqueous solution, extracted three times under reflux, and thenmaintained at 15□ for 1 day. Then, the solution was filtered throughfilter cloth and centrifuged into the residue and a filtrate, and theseparated filtrate was concentrated under reduced pressure, thusobtaining an extract of alcohol steamed Terminalia chebula Retz flesh.

Example 1-5 Preparation of Gingered Terminalia chebula Retz Flesh

Fresh ginger was pulverized, added to a two-fold volume of water,pressed and then juiced. This was repeated 2-3 times to prepare a gingerjuice. 100-150 g of the ginger juice was uniformly sprayed onto 1 kg ofTerminalia chebula Retz flesh, and as the plant was impregnated with theginger plant, it was roasted in a vessel at 100-180□ for 10 minutes to 1hour, and then dried in the shade. The dried material was added to 5 Lof 80% ethanol aqueous solution, extracted three times under reflux, andthen maintained at 15□ for 1 day. Then, the solution was filteredthrough filter cloth and centrifuged into the residue and a filtrate,and the separated filtrate was concentrated under reduced pressure, thusobtaining an extract of gingered Terminalia chebula Retz flesh.

Example 1-6 Preparation of Honeyed Terminalia chebula Retz Flesh

1 kg of dried Terminalia chebula Retz flesh was sufficiently absorbedwith 200-300 g of honey, and was then roasted at 100-160□ for 10 minutesto 1 hour and dried in the shade. The dried plant was added to 5 L of80% ethanol aqueous solution, extracted three times under reflux, andthen maintained at 15□ for 1 day. Then, the solution was filteredthrough filter cloth and centrifuged into the residue and a filtrate,and the separated filtrate was concentrated under reduced pressure, thusobtaining an extract of honeyed Terminalia chebula Retz flesh.

Comparative Examples 2 to 238 Preparation of Unprocessed Medicinal PlantProducts

1 kg of each of the following medicinal plants was treated in the samemanner as in Comparative Example 1, thus obtaining extracts ofComparative Examples 2 to 238 corresponding to the medicinal plants,respecttively:

Dried Pueraria root, Angelica koreana, Chrysanthemum indicum, Rehmanniaeradix, Rhus verniciflua Stokes, licorice, dried ginger, Pharbitidissemen, Cassiae semen, Meliae cortex, Angelica tenuissima, Sophoraflavescens, Caragana chamlagu, Trichosanthes semen, Lycii fructus,Agastache rugosa, Selaginella involvens, Citrus peel, Lonicera japonicaflower, Chrysanthemum zawadskii, Chrysanthemum indicum, Platycodongrandiflorum, Cudrania tricuspidata, Raphani semen, Arisaema amurense,Cervi cornus colla, Phaseolus aureus, antler velvet, Trapa japonicafruit, Brassica rapa, Angelica acutiloba, Citrus grandis osbeck, Circiumjaponicum, Glycine semen germinatum, Datura stramonium, Zizyphus jujuba,Dae-cheong-chow, Rheum undulatum, Persicae semen, Aralia continentalisKitagawa, Cordyceps militaris, Eucommiae cortex, Ephedra sinica,Portulaca oleracea, Rhododendron brachycarpum, Codonopsis pilosulaeradix, malt, Liriopis tuber, Chaenomeles Sinensis fruit, Akebiae caulis,Saussurea lappa, Mui, Moutan cortex radicis, Mentha arvevsis, Bang-pung,Pinellia ternata, Chinese cabbage, Bak-gul-chae, Pulsatilla Koreanaroot, Cynanchi radix, Bletilla striata tuber, Santalum album, Ampelopsisjaponica root, white Poria cocos, Aconitum koreanum, Thujae orientalissemen, Hedyotis diffusa, Paeonia japonica, Angelica dahurica root,Atractylodes macrocephala rhizome, Rubus coreanus fruit, Poria cocos,Arecae pericarpium, Aconiti radix, Allium tuberosum, Ostericumsieboldii, borneol, Sa-kwa-rak, Adenophorae radix, wild ginseng radix,Crataegus pinnatifida fruit, Cornus officianalis fruit, Dioscorearhizoma, Zizyphi spinosi semen, Gardenia fructus, Saururus chinensis,Atractylodes japonica Koidzumi, Sang-gi-saeng, Mori cortex radicis,Dichroa febrifuga, Morus alba leaf, Abrus precatorius, ginger, Rhizomaacori graminei, Agrimonia pilosa ledebour, Seol-kyun-cho, Asarumsieboldi, Perilla frutescens var. acuta, Pinus densiflora, Jasminumfloridum root, Anethum graveolens, Euphorbia lathyris seed, Dipsacusasper, Tricholoma matsutake, Cimicifuga heraclei folia, Bupleurumfalcatum, Massa medicata fermentata, Artemisia leaf, Yakssuk, Lespedezacuneata, Polygonum multiflorum root, Houttuynia cordata, Forsythiafruit, Nelumbinis semen, Nelumbo nucifera seed, Litchi chinensis,Papaver somniferum flower, Ganoderma lucidum, Aconitum carmichaeli,Acanthopanax sessiliflorus bark, Schizandra chinensis fruit, ChinensisGalla, Evodia officinalis, Linderae radix, Maydis stigmata, Polygonatumodoratum root, Orostachys japonicus, Solani nigri herba, Gentiana scabraBUNGE, Euphoria longana testa, Achyranthes japonica root, Polygalaeradix, Genkwa flos, Oenothera odorata, Clematis mandshurica, Ulmiradicis cortex, Brassica campestris, Cistanche deserticola stem,Gypsophila oldhamiana root, Eumn-yang-qwak, Coicis semen, Ik-mo-cho,Alpinia oxyphylla fruit, ginseng, In-jin, Angelica acutiloba root,Securinega suffruticosa, Cnidium officinale, Aster root, Lithospermumerythrorhizon, Paeonia, Adenophora triphylla, ilanthus altissima bark,Grifola umbellata, Poria cocos red, Polygonum multiflorum Thunberg, redcabbage, Paeoniae Radix Rubra, Anthriscus sylvestris, Sorbus commixtacortex, Syzygium aromaticum, Gleditsiae fructus, Gleditsiae spina,Lophatherum gracile, Cistanche deserticola, Phyllostachys nigra sheath,Lycium chinensis root, Hovenia dulcis bark, Anemarrhena asphodeloides,Kochiae fructus, Poncirus trifoliate fruit, Sanguisorba officinalis,Rehmannia glutinosa, Aconitum pseudolaeve Nakai, Jin-O-ga-pi,Phyllanthus urinaria, Citrus unshiu peel, Plantaginis semen, Xanthiumstrumarium fruit, Cnidii rhizoma, Gastrodia elata, Asparaguscochinchinensis, Zanthoxyli fructus, Semiaquilegia adoxoides, Opuntiahumifusa, Dioscorea nipponica Makino, Saussurea involucrata,Trichosanthes kirilowii root, Artemisia apiaceae Herba, Amomi tsao-kofructus, Aconiti ciliare tuber, Gardeniae fructus, Celosiae semen,Althaea rosea, Aquillaria agallocha, Taek-ran, Alisma canaliculatum,Ponciri fructus, Smilacis chinae radix, Cuscutae semen, Ligusticumrhizome, Tetrapanacis medulla, Morinda offcinalis How, Tiglii semen,Taraxaci Herba, Typhae pollen, Calypso bulbosa, Polygonum multiflorumtuber, Aeschynomene indica, Armeniacae semen, Helianthus annus seed,Cyperus rotundus, Elsholtzia ciliata, Cedrela sinensis fruit, Typhaorientalis pollen, Scrophulariae radix, Geranium nepalense, Corydalisturtschaminovii, Schizonepeta tenuifolia, Sesamum indicum, Trigonellafoenum-graecum, Cucurbita spp, Acanthopanax giraldii, red ginseng,Kombucha, Herba Trifolii pratensis, Carthamus tinctorius, floralenvelop, Scutellaria baicalensis Georgi, Astragalus membranaceus, Coptischinensis Franch, Polygonatum lasianthum radix, Lindera obtusilobabranch, Phellodendron amurense bark, Magnolia obovata, black Pharbitissemen, and Siegesbeckiae Herba.

Examples 2-1 to 238-1 Preparation of Salted Medicinal Plants

1 kg of each of the following medicinal plants was treated in the samemanner as in Example 1-1, thus obtaining extracts of Examples 2-1 to238-1 corresponding to the medicinal plants, respecttively:

Dried Pueraria root, Angelica koreana, Chrysanthemum indicum, Rehmanniaeradix, Rhus verniciflua Stokes, licorice, dried ginger, Pharbitidissemen, Cassiae semen, Meliae cortex, Angelica tenuissima, Sophoraflavescens, Caragana chamlagu, Trichosanthes semen, Lycii fructus,Agastache rugosa, Selaginella involvens, Citrus peel, Lonicera japonicaflower, Chrysanthemum zawadskii, Chrysanthemum indicum, Platycodongrandiflorum, Cudrania tricuspidata, Raphani semen, Arisaema amurense,Cervi cornus colla, Phaseolus aureus, antler velvet, Trapa japonicafruit, Brassica rapa, Angelica acutiloba, Citrus grandis osbeck, Circiumjaponicum, Glycine semen germinatum, Datura stramonium, Zizyphus jujuba,Dae-cheong-chow, Rheum undulatum, Persicae semen, Aralia continentalisKitagawa, Cordyceps militaris, Eucommiae cortex, Ephedra sinica,Portulaca oleracea, Rhododendron brachycarpum, Codonopsis pilosulaeradix, malt, Liriopis tuber, Chaenomeles Sinensis fruit, Akebiae caulis,Saussurea lappa, Mui, Moutan cortex radicis, Mentha arvevsis, Bang-pung,Pinellia ternata, Chinese cabbage, Bak-gul-chae, Pulsatilla Koreanaroot, Cynanchi radix, Bletilla striata tuber, Santalum album, Ampelopsisjaponica root, white Poria cocos, Aconitum koreanum, Thujae orientalissemen, Hedyotis diffusa, Paeonia japonica, Angelica dahurica root,Atractylodes macrocephala rhizome, Rubus coreanus fruit, Poria cocos,Arecae pericarpium, Aconiti radix, Allium tuberosum, Ostericumsieboldii, borneol, Sa-kwa-rak, Adenophorae radix, wild ginseng radix,Crataegus pinnatifida fruit, Cornus officianalis fruit, Dioscorearhizoma, Zizyphi spinosi semen, Gardenia fructus, Saururus chinensis,Atractylodes japonica Koidzumi, Sang-gi-saeng, Mori cortex radicis,Dichroa febrifuga, Morus alba leaf, Abrus precatorius, ginger, Rhizomaacori graminei, Agrimonia pilosa ledebour, Seol-kyun-cho, Asarumsieboldi, Perilla frutescens var. acuta, Pinus densiflora, Jasminumfloridum root, Anethum graveolens, Euphorbia lathyris seed, Dipsacusasper, Tricholoma matsutake, Cimicifuga heracleifolia, Bupleurumfalcatum, Massa medicata fermentata, Artemisia leaf, Yakssuk, Lespedezacuneata, Polygonum multiflorum root, Houttuynia cordata, Forsythiafruit, Nelumbinis semen, Nelumbo nucifera seed, Litchi chinensis,Papaver somniferum flower, Ganoderma lucidum, Aconitum carmichaeli,Acanthopanax sessiliflorus bark, Schizandra chinensis fruit, ChinensisGalla, Evodia officinalis, Linderae radix, Maydis stigmata, Polygonatumodoratum root, Orostachys japonicus, Solani nigri herba, Gentiana scabraBUNGE, Euphoria longana testa, Achyranthes japonica root, Polygalaeradix, Genkwa flos, Oenothera odorata, Clematis mandshurica, Ulmiradicis cortex, Brassica campestris, Cistanche deserticola stem,Gypsophila oldhamiana root, Eumn-yang-gwak, Coicis semen, Ik-mo-cho,Alpinia oxyphylla fruit, ginseng, In-jin, Angelica acutiloba root,Securinega suffruticosa, Cnidium officinale, Aster root, Lithospermumerythrorhizon, Paeonia, Adenophora triphylla, ilanthus altissima bark,Grifola umbellata, Poria cocos red, Polygonum multiflorum Thunberg, redcabbage, Paeoniae Radix Rubra, Anthriscus sylvestris, Sorbus commixtacortex, Syzygium aromaticum, Gleditsiae fructus, Gleditsiae spina,Lophatherum gracile, Cistanche deserticola, Phyllostachys nigra sheath,Lycium chinensis root, Hovenia dulcis bark, Anemarrhena asphodeloides,Kochiae fructus, Poncirus trifoliate fruit, Sanguisorba officinalis,Rehmannia glutinosa, Aconitum pseudolaeve Nakai, Jin-O-ga-pi,Phyllanthus urinaria, Citrus unshiu peel, Plantaginis semen, Xanthiumstrumarium fruit, Cnidii rhizoma, Gastrodia elata, Asparaguscochinchinensis, Zanthoxyli fructus, Semiaquilegia adoxoides, Opuntiahumifusa, Dioscorea nipponica Makino, Saussurea involucrata,Trichosanthes kirilowii root, Artemisia apiaceae Herba, Amomi tsao-kofructus, Aconiti ciliare tuber, Gardeniae fructus, Celosiae semen,Althaea rosea, Aquillaria agallocha, Taek-ran, Alisma canaliculatum,Ponciri fructus, Smilacis chinae radix, Cuscutae semen, Ligusticumrhizome, Tetrapanacis medulla, Morinda offcinalis How, Tiglii semen,Taraxaci Herba, Typhae pollen, Calypso bulbosa, Polygonum multiflorumtuber, Aeschynomene indica, Armeniacae semen, Helianthus annus seed,Cyperus rotundus, Elsholtzia ciliata, Cedrela sinensis fruit, Typhaorientalis pollen, Scrophulariae radix, Geranium nepalense, Corydalisturtschaminovii, Schizonepeta tenuifolia, Sesamum indicum, Trigonellafoenum-graecum, Cucurbita spp, Acanthopanax giraldii, red ginseng,Kombucha, Herba Trifolii pratensis, Carthamus tinctorius, floralenvelop, Scutellaria baicalensis Georgi, Astragalus membranaceus, Coptischinensis Franch, Polygonatum lasianthum radix, Lindera obtusilobabranch, Phellodendron amurense bark, Magnolia obovata, black Pharbitissemen, and Siegesbeckiae Herba.

Examples 2-2 to 238-2 Preparation of Carbonized Medicinal Plants

1 kg of each of the following medicinal plants was treated in the samemanner as in Example 1-2, thus obtaining extracts of Examples 2-2 to238-2 corresponding to the medicinal plants, respecttively:

Dried Pueraria root, Angelica koreana, Chrysanthemum indicum, Rehmanniaeradix, Rhus verniciflua Stokes, licorice, dried ginger, Pharbitidissemen, Cassiae semen, Meliae cortex, Angelica tenuissima, Sophoraflavescens, Caragana chamlagu, Trichosanthes semen, Lycii fructus,Agastache rugosa, Selaginella involvens, Citrus peel, Lonicera japonicaflower, Chrysanthemum zawadskii, Chrysanthemum indicum, Platycodongrandiflorum, Cudrania tricuspidata, Raphani semen, Arisaema amurense,Cervi cornus colla, Phaseolus aureus, antler velvet, Trapa japonicafruit, Brassica rapa, Angelica acutiloba, Citrus grandis osbeck, Circiumjaponicum, Glycine semen germinatum, Datura stramonium, Zizyphus jujuba,Dae-cheong-chow, Rheum undulatum, Persicae semen, Aralia continentalisKitagawa, Cordyceps militaris, Eucommiae cortex, Ephedra sinica,Portulaca oleracea, Rhododendron brachyrarpum, Codonopsis pilosulaeradix, malt, Liriopis tuber, Chaenomeles Sinensis fruit, Akebiae caulis,Saussurea lappa, Mui, Moutan cortex radicis, Mentha arvensis, Bang-pung,Pinellia ternata, Chinese cabbage, Bak-gul-chae, Pulsatilla Koreanaroot, Cynanchi radix, Bletilla striata tuber, Santalum album, Ampelopsisjaponica root, white Poria cocos, Aconitum koreanum, Thujae orientalissemen, Hedyotis diffusa, Paeonia japonica, Angelica dahurica root,Atractylodes macrocephala rhizome, Rubus coreanus fruit, Poria cocos,Arecae pericarpium, Aconiti radix, Allium tuberosum, Ostericumsieboldii, borneol, Sa-kwa-rak, Adenophorae radix, wild ginseng radix,Crataegus pinnatifida fruit, Cornus officianalis fruit, Dioscorearhizoma, Zizyphi spinosi semen, Gardenia fructus, Saururus chinensis,Atractylodes japonica Koidzumi, Sang-gi-saeng, Mori cortex radicis,Dichroa febrifuga, Morus alba leaf, Abrus precatorius, ginger, Rhizomaacori graminei, Agrimonia pilosa ledebour, Seol-kyun-cho, Asarumsieboldi, Perilla frutescens var. acuta, Pinus densiflora, Jasminumfloridum root, Anethum graveolens, Euphorbia lathyris seed, Dipsacusasper, Tricholoma matsutake, Cimicifuga heracleifolia, Bupleurumfalcatum, Massa medicata fermentata, Artemisia leaf, Yakssuk, Lespedezacuneata, Polygonum multiflorum root, Houttuynia cordata, Forsythiafruit, Nelumbinis semen, Nelumbo nucifera seed, Litchi chinensis,Papaver somniferum flower, Ganoderma lucidum, Aconitum carmichaeli,Acanthopanax sessiliflorus bark, Schizandra chinensis fruit, ChinensisGalla, Evodia officinalis, Linderae radix, Maydis stigmata, Polygonatumodoratum root, Orostachys japonicus, Solani nigri herba, Gentiana scabraBUNGE, Euphoria longana testa, Achyranthes japonica root, Polygalaeradix, Genkwa flos, Oenothera odorata, Clematis mandshurica, Ulmiradicis cortex, Brassica campestris, Cistanche deserticola stem,Gypsophila oldhamiana root, Eumn-yang-qwak, Coicis semen, Ik-mo-cho,Alpinia oxyphylla fruit, ginseng, In-jin, Angelica acutiloba root,Securinega suffruticosa, Cnidium officinale, Aster root, Lithospermumerythrorhizon, Paeonia, Adenophora triphylla, ilanthus altissima bark,Grifola umbellata, Poria cocos red, Polygonum multiflorum Thunberg, redcabbage, Paeoniae Radix Rubra, Anthriscus sylvestris, Sorbus commixtacortex, Syzygium aromaticum, Gleditsiae fructus, Gleditsiae spina,Lophatherum gracile, Cistanche deserticola, Phyllostachys nigra sheath,Lycium chinensis root, Hovenia dulcis bark, Anemarrhena asphodeloides,Kochiae fructus, Poncirus trifoliate fruit, Sanguisorba officinalis,Rehmannia glutinosa, Aconitum pseudolaeve Nakai, Jin-O-ga-pi,Phyllanthus urinaria, Citrus unshiu peel, Plantaginis semen, Xanthiumstrumarium fruit, Cnidii rhizoma, Gastrodia elata, Asparaguscochinchinensis, Zanthoxyli fructus, Semiaquilegia adoxoides, Opuntiahumifusa, Dioscorea nipponica Makino, Saussurea involucrata,Trichosanthes kirilowii root, Artemisia apiaceae Herba, Amomi tsao-kofructus, Aconiti ciliare tuber, Gardeniae fructus, Celosiae semen,Althaea rosea, Aquillaria agallocha, Taek-ran, Alisma canaliculatum,Ponciri fructus, Smilacis chinae radix, Cuscutae semen, Ligusticumrhizome, Tetrapanacis medulla, Morinda offcinalis How, Tiglii semen,Taraxaci Herba, Typhae pollen, Calypso bulbosa, Polygonum multiflorumtuber, Aeschynomene indica, Armeniacae semen, Helianthus annus seed,Cyperus rotundus, Elsholtzia ciliata, Cedrela sinensis fruit, Typhaorientalis pollen, Scrophulariae radix, Geranium nepalense, Corydalisturtschaminovii, Schizonepeta tenuifolia, Sesamum indicum, Trigonellafoenum-graecum, Cucurbita spp, Acanthopanaxl giraldii, red ginseng,Kombucha, Herba Trifolii pratensis, Carthamus tinctorius, floralenvelop, Scutellaria baicalensis Georgi, Astragalus membranaceus, Coptischinensis Franch, Polygonatum lasianthum radix, Lindera obtusilobabranch, Phellodendron amurense bark, Magnolia obovata, black Pharbitissemen, and Siegesbeckiae Herba.

Examples 2-3 to 238-3 Preparation of Vinegared Medicinal Plants

1 kg of each of the following medicinal plants was treated in the samemanner as in Example 1-3, thus obtaining extracts of Examples 2-3 to238-3 corresponding to the medicinal plants, respecttively:

Dried Pueraria root, Angelica koreana, Chrysanthemum indicum, Rehmanniaeradix, Rhus verniciflua Stokes, licorice, dried ginger, Pharbitidissemen, Cassiae semen, Meliae cortex, Angelica tenuissima, Sophoraflavescens, Caragana chamlagu, Trichosanthes semen, Lycii fructus,Agastache rugosa, Selaginella involvens, Citrus peel, Lonicera japonicaflower, Chrysanthemum zawadskii, Chrysanthemum indicum, Platycodongrandiflorum, Cudrania tricuspidata, Raphani semen, Arisaema amurense,Cervi cornus colla, Phaseolus aureus, antler velvet, Trapa japonicafruit, Brassica rapa, Angelica acutiloba, Citrus grandis osbeck, Circiumjaponicum, Glycine semen germinatum, Datura stramonium, Zizyphus jujuba,Dae-cheong-chow, Rheum undulatum, Persicae semen, Aralia continentalisKitagawa, Cordyceps militaris, Eucommiae cortex, Ephedra sinica,Portulaca oleracea, Rhododendron brachycarpum, Codonopsis pilosulaeradix, malt, Liriopis tuber, Chaenomeles Sinensis fruit, Akebiae caulis,Saussurea lappa, Mui, Moutan cortex radicis, Mentha arvevsis, Bang-pung,Pinellia ternata, Chinese cabbage, Bak-gul-chae, Pulsatilla Koreanaroot, Cynanchi radix, Bletilla striata tuber, Santalum album, Ampelopsisjaponica root, white Poria cocos, Aconitum koreanum, Thujae orientalissemen, Hedyotis diffusa, Paeonia japonica, Angelica dahurica root,Atractylodes macrocephala rhizome, Rubus coreanus fruit, Poria cocos,Arecae pericarpium, Aconiti radix, Allium tuberosum, Ostericumsieboldii, borneol, Sa-kwa-rak, Adenophorae radix, wild ginseng radix,Crataegus pinnatifida fruit, Cornus officianalis fruit, Dioscorearhizoma, Zizyphi spinosi semen, Gardenia fructus, Saururus chinensis,Atractylodes japonica Koidzumi, Sang-gi-saeng, Mori cortex radicis,Dichroa febrifuga, Morus alba leaf, Abrus precatorius, ginger, Rhizomaacori graminei, Agrimonia pilosa ledebour, Seol-kyun-cho, Asarumsieboldi, Perilla frutescens var. acuta, Pinus densiflora, Jasminumfloridum root, Anethum graveolens, Euphorbia lathyris seed, Dipsacusasper, Tricholoma matsutake, Cimicifuga heracleifolia, Bupleurumfalcatum, Massa medicata fermentata, Artemisia leaf, Yakssuk, Lespedezacuneata, Polygonum multiflorum root, Houttuynia cordata, Forsythiafruit, Nelumbinis semen, Nelumbo nucifera seed, Litchi chinensis,Papaver somniferum flower, Ganoderma lucidum, Aconitum carmichaeli,Acanthopanax sessiliflorus bark, Schizandra chinensis fruit, ChinensisGalla, Evodia officinalis, Linderae radix, Maydis stigmata, Polygonatumodoratism root, Orostachys japonicus, Solani nigri herba, Gentianascabra BUNGE, Euphoria longana testa, Achyranthes japonica root,Polygalae radix, Genkwa flos, Oenothera odorata, Clematis mandshurica,Ulmi radicis cortex, Brassica campestris, Cistanche deserticola stem,Gypsophila oldhamiana root, Eumn-yang-gwak, Coicis semen, Ik-mo-cho,Alpinia oxyphylla fruit, ginseng, In-jin, Angelica acutiloba root,Securinega suffruticosa, Cnidium officinale, Aster root, Lithospermumerythrorhizon, Paeonia, Adenophora triphylla, ilanthus altissima bark,Grifola umbellata, Poria cocos red, Polygonum multiflorum Thunberg, redcabbage, Paeoniae Radix Rubra, Anthriscus sylvestris, Sorbus commixtacortex, Syzygium aromaticum, Gleditsiae fructus, Gleditsiae spina,Lophatherum gracile, Cistanche deserticola, Phyllostachys nigra sheath,Lycium chinensis root, Hovenia dulcis bark, Anemarrhena asphodeloides,Kochiae fructus, Poncirus trifoliate fruit, Sanguisorba officinalis,Rehmannia glutinosa, Aconitum pseudolaeve Nakai, Jin-O-ga-pi,Phyllanthus urinaria, Citrus unshiu peel, Plantaginis semen, Xanthiumstrumarium fruit, Cnidii rhizoma, Gastrodia elata, Asparaguscochinchinensis, Zanthoxyli fructus, Semiaquilegia adoxoides, Opuntiahumifusa, Dioscorea nipponica Makino, Saussurea involucrata,Trichosanthes kirilowii root, Artemisia apiaceae Herba, Amomi tsao-kofructus, Aconiti ciliare tuber, Gardeniae fructus, Celosiae semen,Althaea rosea, Aquillaria agallocha, Taek-ran, Alisma canaliculatum,Ponciri fructus, Smilacis chinae radix, Cuscutae semen, Ligusticumrhizome, Tetrapanacis medulla, Morinda offcinalis How, Tiglii semen,Taraxaci Herba, Typhae pollen, Calypso bulbosa, Polygonum multiflorumtuber, Aeschynomene indica, Armeniacae semen, Helianthus annus seed,Cyperus rotundus, Elsholtzia ciliata, Cedrela sinensis fruit, Typhaorientalis pollen, Scrophulariae radix, Geranium nepalense, Corydalisturtschaminovii, Schizonepeta tenuifolia, Sesamum indicum, Trigonellafoenum-graecum, Cucurbita spp, Acanthopanax giraldii, red ginseng,Kombucha, Herba Trifolii pratensis, Carthamus tinctorius, floralenvelop, Scutellaria baicalensis Georgi, Astragalus membranaceus, Coptischinensis Franch, Polygonatum lasianthum radix, Lindera obtusilobabranch, Phellodendron amurense bark, Magnolia obovata, black Pharbitissemen, and Siegesbeckiae Herba.

Examples 2-4 to 238-4 Preparation of Alcohol Steamed Medicinal Plants

1 kg of each of the following medicinal plants was treated in the samemanner as in Example 1-4, thus obtaining extracts of Examples 2-4 to238-4 corresponding to the medicinal plants, respecttively:

Dried Pueraria root, Angelica koreana, Chrysanthemum indicum, Rehmanniaeradix, Rhus verniciflua Stokes, licorice, dried ginger, Pharbitidissemen, Cassiae semen, Meliae cortex, Angelica tenuissima, Sophoraflavescens, Caragana chamlagu, Trichosanthes semen, Lycii fructus,Agastache rugosa, Selaginella involvens, Citrus peel, Lonicera japonicaflower, Chrysanthemum zawadskii, Chrysanthemum indicum, Platycodongrandiflorum, Cudrania tricuspidata, Raphani semen, Arisaema amurense,Cervi cornus colla, Phaseolus aureus, antler velvet, Trapa japonicafruit, Brassica rapa, Angelica acutiloba, Citrus grandis osbeck, Circiumjaponicum, Glycine semen germinatum, Datura stramonium, Zizyphus jujuba,Dae-cheong-chow, Rheum undulatum, Persicae semen, Aralia continentalisKitagawa, Cordyceps militaris, Eucommiae cortex, Ephedra sinica,Portulaca oleracea, Rhododendron brachycarpum, Codonopsis pilosulaeradix, malt, Liriopis tuber, Chaenomeles Sinensis fruit, Akebiae caulis,Saussurea lappa, Mui, Moutan cortex radicis, Mentha arvevsis, Bang-pung,Pinellia ternata, Chinese cabbage, Bak-gul-chae, Pulsatilla Koreanaroot, Cynanchi radix, Bletilla striata tuber, Santalum album, Ampelopsisjaponica root, white Poria cocos, Aconitum koreanum, Thujae orientalissemen, Hedyotis diffusa, Paeonia japonica, Angelica dahurica root,Atractylodes macrocephala rhizome, Rubus coreanus fruit, Poria cocos,Arecae pericarpium, Aconiti radix, Allium tuberosum, Ostericumsieboldii, borneol, Sa-kwa-rak, Adenophorae radix, wild ginseng radix,Crataegus pinnatifida fruit, Cornus officianalis fruit, Dioscorearhizoma, Zizyphi spinosi semen, Gardenia fructus, Saururus chinensis,Atractylodes japonica Koidzumi, SangLigi-saeng, Mori cortex radicis,Dichroa febrifuga, Morus alba leaf, Abrus precatorius, ginger, Rhizomaacori graminei, Agrimonia pilosa ledebour, Seol-kyun-cho, Asarumsieboldi, Perilla frutescens var. acuta, Pinus densiflora, Jasminumfloridum root, Anethum graveolens, Euphorbia lathyris seed, Dipsacusasper, Tricholoma matsutake, Cimicifuga heracleifolia, Bupleurumfalcatum, Massa medicata fermentata, Artemisia leaf, Yakssuk, Lespedezacuneata, Polygonum multiflorum root, Houttuynia cordata, Forsythiafruit, Nelumbinis semen, Nelumbo nucifera seed, Litchi chinensis,Papaver somniferum flower, Ganoderma lucidum, Aconitum carmichaeli,Acanthopanax sessiliflorus bark, Schizandra chinensis fruit, ChinensisGalla, Evodia officinalis, Linderae radix, Maydis stigmata, Polygonatumodoratum root, Orostachys japonicus, Solani nigri herba, Gentiana scabraBUNGE, Euphoria longana testa, Achyranthes japonica root, Polygalaeradix, Genkwa flos, Oenothera odorata, Clematis mandshurica, Ulmiradicis cortex, Brassica campestris, Cistanche deserticola stem,Gypsophila oldhamiana root, Eumn-yang-gwak, Coicis semen, Ik-mo-cho,Alpinia oxyphylla fruit, ginseng, In-jin, Angelica acutiloba root,Securinega suffruticosa, Cnidium officinale, Aster root, Lithospermumerythrorhizon, Paeonia, Adenophora triphylla, ilanthus altissima bark,Grifola umbellata, Poria cocos red, Polygonum multiflorum Thunberg, redcabbage, Paeoniae Radix Rubra, Anthriscus sylvestris, Sorbus commixtacortex, Syzygium aromaticum, Gleditsiae fructus, Gleditsiae spina,Lophatherum gracile, Cistanche deserticola, Phyllostachys nigra sheath,Lycium chinensis root, Hovenia dulcis bark, Anemarrhena asphodeloides,Kochiae fructus, Poncirus trifoliate fruit, Sanguisorba officinalis,Rehmannia glutinosa, Aconitum pseudolaeve Nakai, Jin-O-ga-pi,Phyllanthus urinaria, Citrus unshiu peel, Plantaginis semen, Xanthiumstrumarium fruit, Cnidii rhizoma, Gastrodia elata, Asparaguscochinchinensis, Zanthoxyli fructus, Semiaquilegia adoxoides, Opuntiahumifusa, Dioscorea nipponica Makino, Saussurea involucrata,Trichosanthes kirilowii root, Artemisia apiaceae Herba, Amomi tsao-kofructus, Aconiti ciliare tuber, Gardeniae fructus, Celosiae semen,Althaea rosea, Aquillaria agallocha, Taek-ran, Alisma canaliculatum,Ponciri fructus, Smilacis chinae radix, Cuscutae semen, Ligusticumrhizome, Tetrapanacis medulla, Morinda offcinalis How, Tiglii semen,Taraxaci Herba, Typhae pollen, Calypso bulbosa, Polygonum multiflorumtuber, Aeschynomene indica, Armeniacae semen, Helianthus annus seed,Cyperus rotundus, Elsholtzia ciliata, Cedrela sinensis fruit, Typhaorientalis pollen, Scrophulariae radix, Geranium nepalense, Corydalisturtschaminovii, Schizonepeta tenui folia, Sesamum indicum, Trigonellafoenum-graecum, Cucurbita spp, Acanthopanax giraldii, red ginseng,Kombucha, Herba Trifolii pratensis, Carthamus tinctorius, floralenvelop, Scutellaria baicalensis Georgi, Astragalus membranaceus, Coptischinensis Franch, Polygonatum lasianthum radix, Lindera obtusilobabranch, Phellodendron amurense bark, Magnolia obovata, black Pharbitissemen, and Siegesbeckiae Herba.

Examples 2-5 to 238-5 Preparation of Gingered Medicinal Plants

1 kg of each of the following medicinal plants was treated in the samemanner as in Example 1-5, thus obtaining extracts of Examples 2-5 to238-5 corresponding to the medicinal plants, respecttively:

Dried Pueraria root, Angelica koreana, Chrysanthemum indicum, Rehmanniaeradix, Rhus verniciflua Stokes, licorice, dried ginger, Pharbitidissemen, Cassiae semen, Mediae cortex, Angelica tenuissima, Sophoraflavescens, Caragana chamlagu, Trichosanthes semen, Lycii fructus,Agastache rugosa, Selaginella involvens, Citrus peel, Lonicera japonicaflower, Chrysanthemum zawadskii, Chrysanthemum indicum, Platycodongrandiflorum, Cudrania tricuspidata, Raphani semen, Arisaema amurense,Cervi cornus colla, Phaseolus aureus, antler velvet, Trapa japonicafruit, Brassica rapa, Angelica acutiloba, Citrus grandis osbeck, Circiumjaponicum, Glycine semen germinatum, Datura stramonium, Zizyphus jujuba,Dae-cheong-chow, Rheum undulatum, Persicae semen, Aralia continentalisKitagawa, Cordyceps militaris, Eucommiae cortex, Ephedra sinica,Portulaca oleracea, Rhododendron brachycarpum, Codonopsis pilosulaeradix, malt, Liriopis tuber, Chaenomeles Sinensis fruit, Akebiae caulis,Saussurea lappa, Mui, Moutan cortex radicis, Mentha arvevsis, Bang-pung,Pinellia ternata, Chinese cabbage, Bak-gul-chae, Pulsatilla Koreanaroot, Cynanchi radix, Bletilla striata tuber, Santalum album, Ampelopsisjaponica root, white Poria cocos, Aconitum koreanum, Thujae orientalissemen, Hedyotis diffusa, Paeonia japonica, Angelica dahurica root,Atractydodes macrocephala rhizome, Rubus coreanus fruit, Poria cocos,Arecae pericarpium, Aconiti radix, Allium tuberosum, Ostericumsieboldii, borneol, Sa-kwa-rak, Adenophorae radix, wild ginseng radix,Crataegus pinnatifida fruit, Cornus officianalis fruit, Dioscorearhizoma, Zizyphi spinosi semen, Gardenia fructus, Saururus chinensis,Atractylodes japonica Koidzumi, Sang-gi-saeng, Mori cortex radicis,Dichroa febrifuga, Morus alba leaf, Abrus precatorius, ginger, Rhizomaacori graminei, Agrimonia pilosa ledebour, Seol-kyun-cho, Asarumsieboldi, Perilla frutescens var. acuta, Pinus densiflora, Jasminumfloridum root, Anethum graveolens, Euphorbia lathyris seed, Dipsacusasper, Tricholoma matsutake, Cimicifuga heracleifolia, Bupleurumfalcatum, Massa medicata fermentata, Artemisia leaf, Yakssuk, Lespedezacuneata, Polygonum multiflorum root, Houttuynia cordata, Forsythiafruit, Nelumbinis semen, Nelumbo nucifera seed, Litchi chinensis,Papaver somniferum flower, Ganoderma lucidum, Aconitum carmichaeli,Acanthopanax sessiliflorus bark, Schizandra chinensis fruit, ChinensisGalla, Evodia officinalis, Linderae radix, Maydis stigmata, Polygonatumodoratum root, Orostachys japonicus, Solani nigri herba, Gentiana scabraBUNGE, Euphoria longana testa, Achyranthes japonica root, Polygalaeradix, Genkwa flos, Oenothera odorata, Clematis mandshurica, Ulmiradicis cortex, Brassica campestris, Cistanche deserticola stem,Gypsophila oldhamiana root, Eumn-yang-clwak, Coicis semen, Ik-mo-cho,Alpinia oxyphylla fruit, ginseng, In-jin, Angelica acutiloba root,Securinega suffruticosa, Cnidium officinale, Aster root, Lithospermumerythrorhizon, Paeonia, Adenophora triphylla, ilanthus altissima bark,Grifola umbellata, Poria cocos red, Polygonum multiflorum Thunberg, redcabbage, Paeoniae Radix Rubra, Anthriscus sylvestris, Sorbus commixtacortex, Syzygium aromaticum, Gleditsiae fructus, Gleditsiae spina,Lophatherum gracile, Cistanche deserticola, Phyllostachys nigra sheath,Lycium chinensis root, Hovenia dulcis bark, Anemarrhena asphodeloides,Kochiae fructus, Poncirus trifoliate fruit, Sanguisorba officinalis,Rehmannia glutinosa, Aconitum pseudolaeve Nakai, Jin-O-ga-pi,Phyllanthus urinaria, Citrus unshiu peel, Plantaginis semen, Xanthiumstrumarium fruit, Cnidii rhizoma, Gastrodia elata, Asparaguscochinchinensis, Zanthoxyli fructus, Semiaquilegia adoxoides, Opuntiahumifusa, Dioscorea nipponica Makino, Saussurea involucrata,Trichosanthes kirilowii root, Artemisia apiaceae Herba, Amomi tsao-kofructus, Aconiti ciliare tuber, Gardeniae fructus, Celosiae semen,Althaea rosea, Aquillaria agallocha, Taek-ran, Alisma canaliculatum,Ponciri fructus, Smilacis chinae radix, Cuscutae semen, Ligusticumrhizome, Tetrapanacis medulla, Morinda offcinalis How, Tiglii semen,Taraxaci Herba, Typhae pollen, Calypso bulbosa, Polygonum multiflorumtuber, Aeschynomene indica, Armeniacae semen, Helianthus annus seed,Cyperus rotundus, Elsholtzia ciliata, Cedrela sinensis fruit, Typhaorientalis pollen, Scrophulariae radix, Geranium nepalense, Corydalisturtschaminovii, Schizonepeta tenuifolia, Sesamum indicum, Trigonellafoenum-graecum, Cucurbita spp, Acanthopanax giraldii, red ginseng,Kombucha, Herba Trifolii pratensis, Carthamus tinctorius, floralenvelop, Scutellaria baicalensis Georgi, Astragalus membranaceus, Coptischinensis Franch, Polygonatum lasianthum radix, Lindera obtusilobabranch, Phellodendron amurense bark, Magnolia obovata, black Pharbitissemen, and Siegesbeckiae Herba.

Examples 2-6 to 238-6 Preparation of Honeyed Medicinal Plants

1 kg of each of the following medicinal plants was treated in the samemanner as in Example 1-6, thus obtaining extracts of Examples 2-6 to238-6 corresponding to the medicinal plants, respecttively:

Dried Pueraria root, Angelica koreana, Chrysanthemum indicum, Rehmanniaeradix, Rhus verniciflua Stokes, licorice, dried ginger, Pharbitidissemen, Cassiae semen, Meliae cortex, Angelica tenuissima, Sophoraflavescens, Caragana chamlagu, Trichosanthes semen, Lycii fructus,Agastache rugosa, Selaginella involvens, Citrus peel, Lonicera japonicaflower, Chrysanthemum zawadskii, Chrysanthemum indicum, Platycodongrandiflorum, Cudrania tricuspidata, Raphani semen, Arisaema amurense,Cervi cornus colla, Phaseolus aureus, antler velvet, Trapa japonicafruit, Brassica rapa, Angelica acutiloba, Citrus grandis osbeck, Circiumjaponicum, Glycine semen germinatum, Datura stramonium, Zizyphus jujuba,Dae-cheong-chow, Rheum undulatum, Persicae semen, Aralia continentalisKitagawa, Cordyceps militaris, Eucommiae cortex, Ephedra sinica,Portulaca oleracea, Rhododendron brachycarpum, Codonopsis pilosulaeradix, malt, Liriopis tuber, Chaenomeles Sinensis fruit, Akebiae caulis,Saussurea lappa, Mui, Moutan cortex radicis, Mentha arvevsis, Bang-pung,Pinellia ternata, Chinese cabbage, Bak-gul-chae, Pulsatilla Koreanaroot, Cynanchi radix, Bletilla striata tuber, Santalum album, Ampelopsisjaponica root, white Poria cocos, Aconitum koreanum, Thujae orientalissemen, Hedyotis diffusa, Paeonia japonica, Angelica dahurica root,Atractylodes macrocephala rhizome, Rubus coreanus fruit, Poria cocos,Arecae pericarpium, Aconiti radix, Allium tuberosum, Ostericumsieboldii, borneol, Sa-kwa-rak, Adenophorae radix, wild ginseng radix,Crataegus pinnatifida fruit, Cornus officianalis fruit, Dioscorearhizoma, Zizyphi spinosi semen, Gardenia fructus, Saururus chinensis,Atractylodes japonica Koidzumi, Sang-gi-saeng, Mori cortex radicis,Dichroa febrifuga, Morus alba leaf, Abrus precatorius, ginger, Rhizomaacori graminei, Agrimonia pilosa ledebour, Seol-kyun-cho, Asarumsieboldi, Perilla frutescens var. acuta, Pinus densiflora, Jasminumfloridum root, Anethum graveolens, Euphorbia lathyris seed, Dipsacusasper, Tricholoma matsutake, Cimicifuga heracleifolia, Bupleurumfalcatum, Massa medicata fermentata, Artemisia leaf, Yakssuk, Lespedezacuneata, Polygonum multiflorum root, Houttuynia cordata, Forsythiafruit, Nelumbinis semen, Nelumbo nucifera seed, Litchi chinensis,Papaver somniferum flower, Ganoderma lucidum, Aconitum carmichaeli,Acanthopanax sessiliflorus bark, Schizandra chinensis fruit, ChinensisGalla, Evodia officinalis, Linderae radix, Maydis stigmata, Polygonatumodoratum root, Orostachys japonicus, Solani nigri herba, Gentiana scabraBUNGE, Euphoria longana testa, Achyranthes japonica root, Polygalaeradix, Genkwa flos, Oenothera odorata, Clematis mandshurica, Ulmiradicis cortex, Brassica campestris, Cistanche deserticola stem,Gypsophila oldhamiana root, Eumn-yang-qwak, Coicis semen, Ik-mo-cho,Alpinia oxyphylla fruit, ginseng, In-jin, Angelica acutiloba root,Securinega suffruticosa, Cnidium officinale, Aster root, Lithospermumerythrorhizon, Paeonia, Adenophora triphylla, ilanthus altissima bark,Grifola umbellata, Poria cocos red, Polygonum multiflorum Thunberg, redcabbage, Paeoniae Radix Rubra, Anthriscus sylvestris, Sorbus commixtacortex, Syzygium aromaticum, Gleditsiae fructus, Gleditsiae spina,Lophatherum gracile, Cistanche deserticola, Phyllostachys nigra sheath,Lycium chinensis root, Hovenia dulcis bark, Anemarrhena asphodeloides,Kochiae fructus, Poncirus trifoliate fruit, Sanguisorba officinalis,Rehmannia glutinosa, Aconitum pseudolaeve Nakai, Jin-O-ga-pi,Phyllanthus urinaria, Citrus unshiu peel, Plantaginis semen, Xanthiumstrumarium fruit, Cnidii rhizoma, Gastrodia elata, Asparaguscochinchinensis, Zanthoxyli fructus, Semiaquilegia adoxoides, Opuntiahumifusa, Dioscorea nipponica Makino, Saussurea involucrata,Trichosanthes kirilowii root, Artemisia apiaceae Herba, Amomi tsao-kofructus, Aconiti ciliare tuber, Gardeniae fructus, Celosiae semen,Althaea rosea, Aquillaria agallocha, Taek-ran, Alisma canaliculatum,Ponciri fructus, Smilacis chinae radix, Cuscutae semen, Ligusticumrhizome, Tetrapanacis medulla, Morinda offcinalis How, Tiglii semen,Taraxaci Herba, Typhae pollen, Calypso bulbosa, Polygonum multiflorumtuber, Aeschynomene indica, Armeniacae semen, Helianthus annus seed,Cyperus rotundus, Elsholtzia ciliata, Cedrela sinensis fruit, Typhaorientalis pollen, Scrophulariae radix, Geranium nepalense, Corydalisturtschaminovii, Schizonepeta tenuifolia, Sesamum indicum, Trigonellafoenum-graecum, Cucurbita spp, Acanthopanax giraldii, red ginseng,Kombucha, Herba Trifolii pratensis, Carthamus tinctorius, floralenvelop, Scutellaria baicalensis Georgi, Astragalus membranaceus, Coptischinensis Franch, Polygonatum lasianthum radix, Lindera obtusilobabranch, Phellodendron amurense bark, Magnolia obovata, black Pharbitissemen, and Siegesbeckiae Herba.

Test Example 1 Antioxidant Effect Test (DPPH Test)

Antioxidant activity was evaluated by the change in absorbance resultingfrom the reduction of the organic radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH), (an antioxidant was oxidized). The degree of areduction in absorbance as compared to the control group due to theinhibition of DPPH oxidation in each of the extracts of processedproducts of Examples and the extracts of unprocessed products ofComparative Examples was measured, and the concentration showing anabsorbance which was 50% lower than that of the control group wasrecorded as effective antioxidant concentration.

190 μl of 100 μM DPPH solution in ethanol was mixed with 10 μl of eachof the materials prepared in Examples and Comparative Examples and acontrol sample to make a reaction solution. Each of the reactionsolutions was allowed to react at 37□ for 30 minutes, and then measuredfor absorbance at 540 nm. As the control sample, the syntheticantioxidant Trolox was used. DPPH analysis results for each of thematerials are shown in Tables 1 to 12 below. In Tables, IC₅₀ means thesample concentration at which the absorbance was reduced by 50% due tothe addition of the sample.

TABLE 1 DPPH analysis results (inhibition %) Sample IC₅₀(ppm) Trolox 45Comp. Exam. 1 180 Example 1-1 40 Example 1-2 44 Example 1-3 36 Example1-4 31 Example 1-5 37 Example 1-6 41 Comp. Exam. 2 160 Example 2-1 30Example 2-2 44 Example 2-3 35 Example 2-4 37 Example 2-5 23 Example 2-634 Comp. Exam. 3 240 Example 3-1 45 Example 3-2 42 Example 3-3 34Example 3-4 21 Example 3-5 47 Example 3-6 41 Comp. Exam. 4 135 Example4-1 37 Example 4-2 23 Example 4-3 34 Example 4-4 37 Example 4-5 23Example 4-6 34 Comp. Exam. 5 123 Example 5-1 31 Example 5-2 44 Example5-3 33 Example 5-4 37 Example 5-5 56 Example 5-6 23 Comp. Exam. 6 174Example 6-1 45 Example 6-2 42 Example 6-3 44 Example 6-4 33 Example 6-537 Example 6-6 56 Comp. Exam. 7 166 Example 7-1 37 Example 7-2 37Example 7-3 23 Example 7-4 34 Example 7-5 23 Example 7-6 34 Comp. Exam.8 173 Example 8-1 31 Example 8-2 44 Example 8-3 73 Example 8-4 37Example 8-5 56 Example 8-6 23 Comp. Exam. 9 184 Example 9-1 40 Example9-2 42 Example 9-3 44 Example 9-4 33 Example 9-5 37 Example 9-6 56 Comp.Exam. 10 121 Example 10-1 37 Example 10-2 33 Example 10-3 23 Example10-4 34 Example 10-5 23 Example 10-6 34 Comp. Exam. 11 165 Example 11-130 Example 11-2 44 Example 11-3 35 Example 11-4 31 Example 11-5 23Example 11-6 34 Comp. Exam. 12 115 Example 12-1 45 Example 12-2 42Example 12-3 34 Example 12-4 21 Example 12-5 46 Example 12-6 41 Comp.Exam. 13 135 Example 13-1 37 Example 13-2 34 Example 13-3 37 Example13-4 37 Example 13-5 23 Example 13-6 34 Comp. Exam. 14 123 Example 14-121 Example 14-2 44 Example 14-3 79 Example 14-4 37 Example 14-5 56Example 14-6 23 Comp. Exam. 15 243 Example 15-1 37 Example 15-2 23Example 15-3 34 Example 15-4 37 Example 15-5 23 Example 15-6 34 Comp.Exam. 16 153 Example 16-1 31 Example 16-2 44 Example 16-3 33 Example16-4 37 Example 16-5 56 Example 16-6 23 Comp. Exam. 17 211 Example 17-145 Example 17-2 42 Example 17-3 44 Example 17-4 33 Example 17-5 37Example 17-6 56 Comp. Exam. 18 142 Example 18-1 40 Example 18-2 42Example 18-3 44 Example 18-4 33 Example 18-5 37 Example 18-6 56 Comp.Exam. 19 229 Example 19-1 37 Example 19-2 33 Example 19-3 23 Example19-4 34 Example 19-5 23 Example 19-6 34 Comp. Exam. 20 224 Example 20-131 Example 20-2 44 Example 20-3 33 Example 20-4 37 Example 20-5 56Example 20-6 23 Comp. Exam. 21 104 Example 21-1 45 Example 21-2 42Example 21-3 44 Example 21-4 33 Example 21-5 37 Example 21-6 56

TABLE 2 Sample IC₅₀(ppm) Comp. Exam. 22 123 Example 22-1 31 Example 22-244 Example 22-3 73 Example 22-4 37 Example 22-5 56 Example 22-6 23 Comp.Exam. 23 143 Example 23-1 40 Example 23-2 42 Example 23-3 44 Example23-4 33 Example 23-5 37 Example 23-6 56 Comp. Exam. 24 121 Example 24-137 Example 24-2 33 Example 24-3 23 Example 24-4 34 Example 24-5 23Example 24-6 34 Comp. Exam. 25 155 Example 25-1 30 Example 25-2 44Example 25-3 35 Example 25-4 31 Example 25-5 23 Example 2-6 34 Comp.Exam. 26 165 Example 26-1 45 Example 26-2 42 Example 26-3 34 Example26-4 21 Example 26-5 46 Example 26-6 41 Comp. Exam. 27 115 Example 27-137 Example 27-2 34 Example 27-3 32 Example 27-4 37 Example 27-5 23Example 27-6 34 Comp. Exam. 28 126 Example 28-1 21 Example 28-2 44Example 28-3 79 Example 28-4 37 Example 28-5 22 Example 28-6 23 Comp.Exam. 29 180 Example 29-1 40 Example 29-2 44 Example 29-3 36 Example29-4 31 Example 29-5 37 Example 29-6 41 Comp. Exam. 30 160 Example 30-130 Example 30-2 44 Example 30-3 35 Example 30-4 37 Example 30-5 23Example 30-6 34 Comp. Exam. 31 222 Example 31-1 45 Example 31-2 42Example 31-3 34 Example 31-4 21 Example 31-5 47 Example 31-6 41 Comp.Exam. 32 135 Example 32-1 37 Example 32-2 23 Example 32-3 34 Example32-4 37 Example 32-5 23 Example 32-6 34 Comp. Exam. 33 332 Example 33-131 Example 33-2 44 Example 33-3 83 Example 33-4 47 Example 33-5 56Example 33-6 23 Comp. Exam. 34 174 Example 34-1 45 Example 34-2 42Example 34-3 44 Example 34-4 55 Example 34-5 37 Example 34-6 56 Comp.Exam. 35 166 Example 35-1 37 Example 35-2 65 Example 35-3 23 Example35-4 34 Example 35-5 23 Example 35-6 34 Comp. Exam. 36 114 Example 36-131 Example 36-2 44 Example 36-3 73 Example 36-4 37 Example 36-5 56Example 36-6 23 Comp. Exam. 37 144 Example 37-1 40 Example 37-2 42Example 37-3 34 Example 37-4 33 Example 37-5 37 Example 37-6 56 Comp.Exam. 38 134 Example 38-1 37 Example 38-2 33 Example 38-3 54 Example38-4 34 Example 38-5 23 Example 38-6 34 Comp. Exam. 39 143 Example 39-130 Example 39-2 44 Example 39-3 35 Example 39-4 31 Example 39-5 23Example 39-6 34 Comp. Exam. 40 176 Example 40-1 45 Example 40-2 42Example 40-3 53 Example 40-4 21 Example 40-5 46 Example 40-6 41 Comp.Exam. 41 235 Example 41-1 37 Example 41-2 34 Example 41-3 44 Example41-4 65 Example 41-5 23 Example 41-6 34 Comp. Exam. 42 123 Example 42-121 Example 42-2 44 Example 42-3 69 Example 42-4 37 Example 42-5 56Example 42-6 47

TABLE 3 Sample IC₅₀(ppm) Comp. Exam. 43 133 Example 43-1 40 Example 43-244 Example 43-3 36 Example 43-4 31 Example 43-5 37 Example 43-6 41 Comp.Exam. 44 160 Example 44-1 30 Example 44-2 44 Example 44-3 35 Example44-4 37 Example 44-5 13 Example 44-6 34 Comp. Exam. 45 222 Example 45-145 Example 45-2 42 Example 45-3 34 Example 45-4 21 Example 45-5 47Example 45-6 41 Comp. Exam. 46 135 Example 46-1 37 Example 46-2 23Example 46-3 34 Example 46-4 55 Example 46-5 23 Example 46-6 34 Comp.Exam. 47 332 Example 47-1 31 Example 47-2 44 Example 47-3 83 Example47-4 55 Example 47-5 56 Example 47-6 23 Comp. Exam. 48 174 Example 48-145 Example 48-2 42 Example 48-3 43 Example 48-4 55 Example 48-5 37Example 48-6 56 Comp. Exam. 49 166 Example 49-1 37 Example 49-2 65Example 49-3 23 Example 49-4 34 Example 49-5 23 Example 49-6 34 Comp.Exam. 50 143 Example 50-1 37 Example 50-2 23 Example 50-3 34 Example50-4 37 Example 50-5 23 Example 50-6 34 Comp. Exam. 51 153 Example 51-131 Example 51-2 44 Example 51-3 65 Example 51-4 37 Example 51-5 56Example 51-6 23 Comp. Exam. 52 211 Example 52-1 45 Example 52-2 42Example 52-3 44 Example 52-4 33 Example 52-5 37 Example 52-6 56 Comp.Exam. 53 142 Example 53-1 40 Example 53-2 42 Example 53-3 44 Example53-4 33 Example 53-5 37 Example 53-6 56 Comp. Exam. 54 229 Example 54-137 Example 54-2 33 Example 54-3 23 Example 54-4 43 Example 54-5 23Example 54-6 34 Comp. Exam. 55 224 Example 55-1 31 Example 55-2 44Example 55-3 65 Example 55-4 37 Example 55-5 56 Example 55-6 23 Comp.Exam. 56 104 Example 56-1 45 Example 56-2 42 Example 56-3 55 Example56-4 33 Example 56-5 37 Example 56-6 56 Comp. Exam. 57 175 Example 57-130 Example 57-2 44 Example 57-3 35 Example 57-4 43 Example 57-5 23Example 57-6 34 Comp. Exam. 58 165 Example 58-1 65 Example 58-2 42Example 58-3 43 Example 58-4 21 Example 58-5 46 Example 58-6 41 Comp.Exam. 59 115 Example 59-1 37 Example 59-2 34 Example 59-3 32 Example59-4 37 Example 59-5 23 Example 59-6 34 Comp. Exam. 60 126 Example 60-133 Example 60-2 44 Example 60-3 79 Example 60-4 37 Example 60-5 22Example 60-6 23 Comp. Exam. 61 160 Example 61-1 30 Example 61-2 44Example 61-3 35 Example 61-4 37 Example 61-5 23 Example 61-6 34 Comp.Exam. 62 222 Example 62-1 45 Example 62-2 42 Example 62-3 34 Example62-4 21 Example 62-5 65 Example 62-6 41 Comp. Exam. 63 224 Example 63-131 Example 63-2 44 Example 63-3 33 Example 63-4 37 Example 63-5 56Example 63-6 23

TABLE 4 Sample IC₅₀(ppm) Comp. Exam. 64 174 Example 64-1 45 Example 64-242 Example 64-3 44 Example 64-4 55 Example 64-5 37 Example 64-6 56 Comp.Exam. 65 166 Example 65-1 37 Example 65-2 65 Example 65-3 23 Example65-4 34 Example 65-5 23 Example 65-6 34 Comp. Exam. 66 222 Example 66-145 Example 66-2 42 Example 66-3 34 Example 66-4 21 Example 66-5 47Example 66-6 41 Comp. Exam. 67 135 Example 67-1 37 Example 67-2 23Example 67-3 34 Example 67-4 55 Example 67-5 23 Example 67-6 34 Comp.Exam. 68 332 Example 68-1 31 Example 68-2 44 Example 68-3 83 Example68-4 55 Example 68-5 56 Example 68-6 23 Comp. Exam. 69 142 Example 69-140 Example 69-2 42 Example 69-3 44 Example 69-4 33 Example 69-5 37Example 69-6 56 Comp. Exam. 70 229 Example 70-1 37 Example 70-2 33Example 70-3 23 Example 70-4 34 Example 70-5 23 Example 70-6 34 Comp.Exam. 71 114 Example 71-1 31 Example 71-2 44 Example 71-3 73 Example71-4 37 Example 71-5 56 Example 71-6 23 Comp. Exam. 72 144 Example 72-140 Example 72-2 42 Example 72-3 34 Example 72-4 33 Example 72-5 37Example 72-6 56 Comp. Exam. 73 134 Example 73-1 37 Example 73-2 33Example 73-3 54 Example 73-4 34 Example 73-5 23 Example 73-6 34 Comp.Exam. 74 143 Example 74-1 30 Example 74-2 44 Example 74-3 35 Example74-4 31 Example 74-5 23 Example 74-6 34 Comp. Exam. 75 176 Example 75-145 Example 75-2 42 Example 75-3 53 Example 75-4 21 Example 75-5 46Example 75-6 41 Comp. Exam. 76 235 Example 76-1 37 Example 76-2 34Example 76-3 44 Example 76-4 65 Example 76-5 23 Example 76-6 34 Comp.Exam. 77 123 Example 77-1 21 Example 77-2 44 Example 77-3 69 Example77-4 37 Example 77-5 56 Example 77-6 47 Comp. Exam. 78 135 Example 78-137 Example 78-2 23 Example 78-3 34 Example 78-4 55 Example 78-5 23Example 78-6 34 Comp. Exam. 79 332 Example 79-1 31 Example 79-2 44Example 79-3 83 Example 79-4 55 Example 79-5 56 Example 79-6 23 Comp.Exam. 80 174 Example 80-1 45 Example 80-2 42 Example 80-3 56 Example80-4 55 Example 80-5 37 Example 80-6 56 Comp. Exam. 81 166 Example 81-137 Example 81-2 65 Example 81-3 23 Example 81-4 34 Example 81-5 23Example 81-6 34 Comp. Exam. 82 160 Example 82-1 30 Example 82-2 44Example 82-3 35 Example 82-4 37 Example 82-5 23 Example 82-6 34 Comp.Exam. 83 222 Example 83-1 45 Example 83-2 42 Example 83-3 34 Example83-4 21 Example 83-5 47 Example 83-6 41 Comp. Exam. 84 135 Example 84-137 Example 84-2 23 Example 84-3 34 Example 84-4 37 Example 84-5 23Example 84-6 34

TABLE 5 Sample IC₅₀(ppm) Comp. Exam. 85 173 Example 85-1 31 Example 85-244 Example 85-3 73 Example 85-4 37 Example 85-5 56 Example 85-6 23 Comp.Exam. 86 173 Example 86-1 40 Example 86-2 42 Example 86-3 44 Example86-4 33 Example 86-5 37 Example 86-6 56 Comp. Exam. 87 121 Example 87-137 Example 87-2 12 Example 87-3 23 Example 87-4 34 Example 87-5 23Example 87-6 34 Comp. Exam. 88 165 Example 88-1 30 Example 88-2 44Example 88-3 35 Example 88-4 31 Example 88-5 23 Example 88-6 34 Comp.Exam. 89 115 Example 89-1 45 Example 89-2 42 Example 89-3 19 Example89-4 21 Example 89-5 46 Example 89-6 41 Comp. Exam. 90 135 Example 90-137 Example 90-2 34 Example 90-3 37 Example 90-4 37 Example 90-5 23Example 90-6 34 Comp. Exam. 91 123 Example 91-1 21 Example 91-2 44Example 91-3 79 Example 91-4 37 Example 91-5 56 Example 91-6 23 Comp.Exam. 92 180 Example 92-1 40 Example 92-2 44 Example 92-3 36 Example92-4 31 Example 92-5 37 Example 92-6 41 Comp. Exam. 93 160 Example 93-130 Example 93-2 54 Example 93-3 35 Example 93-4 37 Example 93-5 23Example 93-6 34 Comp. Exam. 94 240 Example 94-1 45 Example 94-2 42Example 94-3 34 Example 94-4 21 Example 94-5 47 Example 94-6 33 Comp.Exam. 95 135 Example 95-1 37 Example 95-2 23 Example 95-3 34 Example95-4 37 Example 95-5 23 Example 95-6 34 Comp. Exam. 96 123 Example 96-131 Example 96-2 44 Example 96-3 33 Example 96-4 37 Example 96-5 56Example 96-6 23 Comp. Exam. 97 174 Example 97-1 45 Example 97-2 42Example 97-3 44 Example 97-4 33 Example 97-5 37 Example 97-6 56 Comp.Exam. 98 166 Example 98-1 37 Example 98-2 55 Example 98-3 23 Example98-4 34 Example 98-5 23 Example 98-6 34 Comp. Exam. 99 165 Example 99-130 Example 99-2 44 Example 99-3 35 Example 99-4 31 Example 99-5 23Example 99-6 34 Comp. Exam. 100 134 Example 100-1 37 Example 100-2 33Example 100-3 54 Example 100-4 34 Example 100-5 23 Example 100-6 34Comp. Exam. 101 143 Example 101-1 30 Example 101-2 14 Example 101-3 35Example 101-4 31 Example 101-5 23 Example 101-6 34 Comp. Exam. 102 176Example 102-1 45 Example 102-2 42 Example 102-3 53 Example 102-4 21Example 102-5 46 Example 102-6 41 Comp. Exam. 103 235 Example 103-1 37Example 103-2 34 Example 103-3 44 Example 103-4 65 Example 103-5 23Example 103-6 34 Comp. Exam. 104 123 Example 104-1 21 Example 104-2 44Example 104-3 69 Example 104-4 37 Example 104-5 56 Example 104-6 47Comp. Exam. 105 160 Example 105-1 30 Example 105-2 44 Example 105-3 35Example 105-4 35 Example 105-5 23 Example 105-6 34

TABLE 6 Sample IC₅₀(ppm) Comp. Exam. 106 137 Example 106-1 30 Example106-2 44 Example 106-3 35 Example 106-4 37 Example 106-5 23 Example106-6 34 Comp. Exam. 107 121 Example 107-1 37 Example 107-2 33 Example107-3 23 Example 107-4 34 Example 107-5 23 Example 107-6 34 Comp. Exam.108 165 Example 108-1 30 Example 108-2 44 Example 108-3 35 Example 108-431 Example 108-5 23 Example 108-6 34 Comp. Exam. 109 115 Example 109-145 Example 109-2 42 Example 109-3 34 Example 109-4 21 Example 109-5 46Example 109-6 41 Comp. Exam. 110 123 Example 110-1 21 Example 110-2 44Example 110-3 69 Example 110-4 37 Example 110-5 56 Example 110-6 47Comp. Exam. 111 160 Example 111-1 30 Example 111-2 44 Example 111-3 35Example 111-4 37 Example 111-5 23 Example 111-6 34 Comp. Exam. 112 135Example 112-1 37 Example 112-2 34 Example 112-3 37 Example 112-4 37Example 112-5 23 Example 112-6 34 Comp. Exam. 113 144 Example 113-1 40Example 113-2 42 Example 113-3 34 Example 113-4 33 Example 113-5 37Example 113-6 56 Comp. Exam. 114 134 Example 114-1 37 Example 114-2 33Example 114-3 54 Example 114-4 34 Example 114-5 23 Example 114-6 34Comp. Exam. 115 177 Example 115-1 45 Example 115-2 42 Example 115-3 56Example 115-4 55 Example 115-5 37 Example 115-6 56 Comp. Exam. 116 166Example 116-1 37 Example 116-2 65 Example 116-3 23 Example 116-4 34Example 116-5 23 Example 116-6 34 Comp. Exam. 115 160 Example 117-1 30Example 117-2 44 Example 117-3 35 Example 117-4 37 Example 117-5 23Example 117-6 34 Comp. Exam. 118 115 Example 118-1 45 Example 118-2 42Example 118-3 64 Example 118-4 21 Example 118-5 46 Example 118-6 41Comp. Exam. 119 123 Example 119-1 21 Example 119-2 44 Example 119-3 55Example 119-4 37 Example 119-5 56 Example 119-6 47 Comp. Exam. 120 121Example 120-1 37 Example 120-2 33 Example 120-3 23 Example 120-4 34Example 120-5 23 Example 120-6 34 Comp. Exam. 121 165 Example 121-1 30Example 121-2 44 Example 121-3 35 Example 121-4 31 Example 121-5 23Example 121-6 34 Comp. Exam. 122 154 Example 122-1 37 Example 122-2 33Example 122-3 23 Example 122-4 34 Example 122-5 23 Example 122-6 34Comp. Exam. 123 155 Example 123-1 30 Example 123-2 44 Example 123-3 35Example 123-4 31 Example 123-5 23 Example 123-6 34 Comp. Exam. 124 165Example 124-1 45 Example 124-2 42 Example 124-3 34 Example 124-4 21Example 124-5 46 Example 124-6 41 Comp. Exam. 125 123 Example 125-1 31Example 125-2 44 Example 125-3 33 Example 125-4 37 Example 125-5 56Example 125-6 23 Comp. Exam. 126 174 Example 126-1 45 Example 126-2 42Example 126-3 44 Example 126-4 33 Example 126-5 37 Example 126-6 56

TABLE 7 Sample IC₅₀(ppm) Comp. Exam. 127 153 Example 127-1 31 Example127-2 44 Example 127-3 65 Example 127-4 37 Example 127-5 56 Example127-6 23 Comp. Exam. 128 211 Example 128-1 45 Example 128-2 42 Example128-3 44 Example 128-4 33 Example 128-5 37 Example 128-6 56 Comp. Exam.129 129 Example 129-1 40 Example 129-2 42 Example 129-3 44 Example 129-433 Example 129-5 37 Example 129-6 56 Comp. Exam. 130 229 Example 130-137 Example 130-2 33 Example 130-3 23 Example 130-4 43 Example 130-5 23Example 130-6 34 Comp. Exam. 131 224 Example 131-1 31 Example 131-2 44Example 131-3 65 Example 131-4 37 Example 131-5 56 Example 131-6 23Comp. Exam. 132 104 Example 132-1 45 Example 132-2 42 Example 132-3 55Example 132-4 33 Example 132-5 37 Example 132-6 56 Comp. Exam. 133 143Example 133-1 37 Example 133-2 23 Example 133-3 34 Example 133-4 37Example 133-5 23 Example 133-6 34 Comp. Exam. 134 224 Example 134-1 31Example 134-2 44 Example 134-3 65 Example 134-4 37 Example 134-5 56Example 134-6 23 Comp. Exam. 135 104 Example 135-1 45 Example 135-2 42Example 135-3 55 Example 135-4 33 Example 135-5 37 Example 135-6 56Comp. Exam. 136 211 Example 136-1 45 Example 136-2 42 Example 136-3 44Example 136-4 33 Example 136-5 37 Example 136-6 56 Comp. Exam. 137 142Example 137-1 40 Example 137-2 42 Example 137-3 44 Example 137-4 33Example 137-5 37 Example 137-6 56 Comp. Exam. 138 229 Example 138-1 37Example 138-2 33 Example 138-3 23 Example 138-4 43 Example 138-5 23Example 138-6 34 Comp. Exam. 139 123 Example 139-1 21 Example 139-2 44Example 139-3 69 Example 139-4 37 Example 139-5 56 Example 139-6 47Comp. Exam. 140 165 Example 140-1 30 Example 140-2 44 Example 140-3 35Example 140-4 31 Example 140-5 23 Example 140-6 34 Comp. Exam. 141 123Example 141-1 31 Example 141-2 44 Example 141-3 73 Example 141-4 37Example 141-5 56 Example 141-6 23 Comp. Exam. 142 143 Example 142-1 40Example 142-2 42 Example 142-3 44 Example 142-4 33 Example 142-5 37Example 142-6 56 Comp. Exam. 143 121 Example 143-1 37 Example 143-2 33Example 143-3 23 Example 143-4 34 Example 143-5 23 Example 143-6 34Comp. Exam. 144 155 Example 144-1 30 Example 144-2 44 Example 144-3 35Example 144-4 31 Example 144-5 23 Example 144-6 34 Comp. Exam. 145 165Example 145-1 45 Example 145-2 42 Example 145-3 34 Example 145-4 21Example 145-5 46 Example 145-6 41 Comp. Exam. 146 145 Example 146-1 37Example 146-2 34 Example 146-3 32 Example 146-4 37 Example 146-5 23Example 146-6 34 Comp. Exam. 147 134 Example 147-1 21 Example 147-2 44Example 147-3 79 Example 147-4 37 Example 147-5 22 Example 147-6 23

TABLE 8 Sample IC₅₀(ppm) Comp. Exam. 148 141 Example 148-1 37 Example148-2 23 Example 148-3 34 Example 148-4 37 Example 148-5 23 Example148-6 34 Comp. Exam. 149 153 Example 149-1 31 Example 149-2 44 Example149-3 65 Example 149-4 37 Example 149-5 56 Example 149-6 23 Comp. Exam.150 211 Example 150-1 45 Example 150-2 42 Example 150-3 44 Example 150-433 Example 150-5 37 Example 150-6 56 Comp. Exam. 151 142 Example 151-140 Example 151-2 42 Example 151-3 44 Example 151-4 33 Example 151-5 37Example 151-6 56 Comp. Exam. 152 229 Example 152-1 37 Example 152-2 33Example 152-3 23 Example 152-4 43 Example 152-5 23 Example 152-6 34Comp. Exam. 153 224 Example 153-1 31 Example 153-2 44 Example 153-3 65Example 153-4 37 Example 153-5 56 Example 153-6 23 Comp. Exam. 154 104Example 154-1 45 Example 154-2 42 Example 154-3 55 Example 154-4 33Example 154-5 37 Example 154-6 56 Comp. Exam. 155 178 Example 155-1 30Example 155-2 44 Example 155-3 35 Example 155-4 43 Example 155-5 23Example 155-6 34 Comp. Exam. 156 165 Example 156-1 65 Example 156-2 42Example 156-3 43 Example 156-4 21 Example 156-5 46 Example 156-6 41Comp. Exam. 157 115 Example 157-1 37 Example 157-2 34 Example 157-3 32Example 157-4 37 Example 157-5 23 Example 157-6 34 Comp. Exam. 158 126Example 158-1 33 Example 158-2 44 Example 158-3 79 Example 158-4 37Example 158-5 22 Example 158-6 23 Comp. Exam. 159 160 Example 159-1 30Example 159-2 44 Example 159-3 35 Example 159-4 37 Example 159-5 23Example 159-6 34 Comp. Exam. 160 222 Example 160-1 45 Example 160-2 42Example 160-3 34 Example 160-4 21 Example 160-5 65 Example 160-6 41Comp. Exam. 161 224 Example 161-1 31 Example 161-2 44 Example 161-3 33Example 161-4 37 Example 161-5 56 Example 161-6 23 Comp. Exam. 162 137Example 162-1 30 Example 162-2 44 Example 162-3 35 Example 162-4 37Example 162-5 23 Example 162-6 34 Comp. Exam. 163 121 Example 163-1 37Example 163-2 33 Example 163-3 23 Example 163-4 34 Example 163-5 23Example 163-6 34 Comp. Exam. 164 165 Example 164-1 30 Example 164-2 44Example 164-3 35 Example 164-4 31 Example 164-5 23 Example 164-6 34Comp. Exam. 165 115 Example 165-1 45 Example 165-2 42 Example 165-3 34Example 165-4 21 Example 165-5 46 Example 165-6 41 Comp. Exam. 166 123Example 166-1 21 Example 166-2 44 Example 166-3 69 Example 166-4 37Example 166-5 56 Example 166-6 47 Comp. Exam. 167 160 Example 167-1 30Example 167-2 44 Example 167-3 35 Example 167-4 37 Example 167-5 23Example 167-6 34 Comp. Exam. 168 135 Example 168-1 37 Example 168-2 34Example 168-3 37 Example 168-4 37 Example 168-5 23 Example 168-6 34

TABLE 9 Sample IC₅₀(ppm) Comp. Exam. 169 188 Example 169-1 40 Example169-2 24 Example 169-3 36 Example 169-4 31 Example 169-5 37 Example169-6 41 Comp. Exam. 170 160 Example 170-1 30 Example 170-2 44 Example170-3 42 Example 170-4 37 Example 170-5 23 Example 170-6 34 Comp. Exam.171 222 Example 171-1 45 Example 171-2 42 Example 171-3 34 Example 171-421 Example 171-5 47 Example 171-6 41 Comp. Exam. 172 135 Example 172-137 Example 172-2 23 Example 172-3 34 Example 172-4 37 Example 172-5 23Example 172-6 34 Comp. Exam. 173 332 Example 173-1 31 Example 173-2 44Example 173-3 42 Example 173-4 47 Example 173-5 56 Example 173-6 23Comp. Exam. 174 174 Example 174-1 45 Example 174-2 42 Example 174-3 44Example 174-4 55 Example 174-5 37 Example 174-6 56 Comp. Exam. 175 166Example 175-1 37 Example 175-2 65 Example 175-3 23 Example 175-4 24Example 175-5 23 Example 175-6 34 Comp. Exam. 176 137 Example 176-1 30Example 176-2 44 Example 176-3 35 Example 176-4 37 Example 176-5 23Example 176-6 34 Comp. Exam. 177 121 Example 177-1 37 Example 177-2 33Example 177-3 23 Example 177-4 34 Example 177-5 23 Example 177-6 34Comp. Exam. 178 165 Example 178-1 30 Example 178-2 44 Example 178-3 35Example 178-4 31 Example 178-5 23 Example 178-6 34 Comp. Exam. 179 115Example 179-1 45 Example 179-2 42 Example 179-3 34 Example 179-4 21Example 179-5 46 Example 179-6 41 Comp. Exam. 180 123 Example 180-1 21Example 180-2 44 Example 180-3 69 Example 180-4 37 Example 180-5 56Example 180-6 47 Comp. Exam. 181 160 Example 181-1 30 Example 181-2 44Example 181-3 35 Example 181-4 37 Example 181-5 23 Example 181-6 34Comp. Exam. 182 135 Example 182-1 37 Example 182-2 34 Example 182-3 37Example 182-4 37 Example 182-5 23 Example 182-6 34 Comp. Exam. 183 174Example 183-1 31 Example 183-2 44 Example 183-3 65 Example 183-4 37Example 183-5 56 Example 183-6 23 Comp. Exam. 184 104 Example 184-1 45Example 184-2 42 Example 184-3 55 Example 184-4 33 Example 184-5 37Example 184-6 56 Comp. Exam. 185 211 Example 185-1 45 Example 185-2 42Example 185-3 44 Example 185-4 33 Example 185-5 37 Example 185-6 56Comp. Exam. 186 142 Example 186-1 40 Example 186-2 42 Example 186-3 44Example 186-4 33 Example 186-5 37 Example 186-6 56 Comp. Exam. 187 229Example 187-1 37 Example 187-2 33 Example 187-3 23 Example 187-4 43Example 187-5 23 Example 187-6 34 Comp. Exam. 188 123 Example 188-1 21Example 188-2 44 Example 188-3 69 Example 188-4 37 Example 188-5 56Example 188-6 47 Comp. Exam. 189 165 Example 189-1 30 Example 189-2 44Example 189-3 35 Example 189-4 31 Example 189-5 23 Example 189-6 34

TABLE 10 Sample IC₅₀(ppm) Comp. Exam. 190 174 Example 190-1 45 Example190-2 42 Example 190-3 44 Example 190-4 55 Example 190-5 37 Example190-6 56 Comp. Exam. 191 166 Example 191-1 37 Example 191-2 65 Example191-3 23 Example 191-4 34 Example 191-5 23 Example 191-6 34 Comp. Exam.192 222 Example 192-1 45 Example 192-2 42 Example 192-3 34 Example 192-421 Example 192-5 47 Example 192-6 41 Comp. Exam. 193 138 Example 193-137 Example 193-2 23 Example 193-3 34 Example 193-4 55 Example 193-5 23Example 193-6 34 Comp. Exam. 194 332 Example 194-1 31 Example 194-2 44Example 194-3 33 Example 194-4 55 Example 194-5 56 Example 194-6 23Comp. Exam. 195 142 Example 195-1 40 Example 195-2 42 Example 195-3 44Example 195-4 33 Example 195-5 37 Example 195-6 56 Comp. Exam. 196 229Example 196-1 37 Example 196-2 33 Example 196-3 23 Example 196-4 34Example 196-5 23 Example 196-6 34 Comp. Exam. 197 178 Example 197-1 30Example 197-2 44 Example 197-3 35 Example 197-4 43 Example 197-5 23Example 197-6 34 Comp. Exam. 198 165 Example 198-1 65 Example 198-2 42Example 198-3 43 Example 198-4 21 Example 198-5 46 Example 198-6 41Comp. Exam. 199 126 Example 199-1 37 Example 199-2 34 Example 199-3 43Example 199-4 37 Example 199-5 23 Example 199-6 34 Comp. Exam. 200 126Example 200-1 33 Example 200-2 44 Example 200-3 79 Example 200-4 37Example 200-5 22 Example 200-6 23 Comp. Exam. 201 160 Example 201-1 30Example 201-2 44 Example 201-3 35 Example 201-4 37 Example 201-5 34Example 201-6 34 Comp. Exam. 202 222 Example 202-1 45 Example 202-2 42Example 202-3 34 Example 202-4 21 Example 202-5 65 Example 202-6 41Comp. Exam. 203 224 Example 203-1 31 Example 203-2 44 Example 203-3 33Example 203-4 37 Example 203-5 56 Example 203-6 23 Comp. Exam. 204 121Example 204-1 37 Example 204-2 33 Example 204-3 23 Example 204-4 34Example 204-5 23 Example 204-6 34 Comp. Exam. 205 161 Example 205-1 30Example 205-2 44 Example 205-3 35 Example 205-4 31 Example 205-5 23Example 205-6 34 Comp. Exam. 206 154 Example 206-1 37 Example 206-2 33Example 206-3 23 Example 206-4 45 Example 206-5 23 Example 206-6 34Comp. Exam. 207 155 Example 207-1 30 Example 207-2 44 Example 207-3 35Example 207-4 31 Example 207-5 23 Example 207-6 34 Comp. Exam. 208 165Example 208-1 45 Example 208-2 42 Example 208-3 34 Example 208-4 21Example 208-5 46 Example 208-6 41 Comp. Exam. 209 123 Example 209-1 31Example 209-2 44 Example 209-3 33 Example 209-4 37 Example 209-5 56Example 209-6 23 Comp. Exam. 210 174 Example 210-1 45 Example 210-2 42Example 210-3 44 Example 210-4 33 Example 210-5 37 Example 210-6 56

TABLE 11 Sample IC₅₀(ppm) Comp. Exam. 211 133 Example 211-1 31 Example211-2 44 Example 211-3 73 Example 211-4 37 Example 211-5 56 Example211-6 23 Comp. Exam. 212 184 Example 212-1 40 Example 212-2 42 Example212-3 44 Example 212-4 33 Example 212-5 37 Example 212-6 56 Comp. Exam.213 121 Example 213-1 37 Example 213-2 33 Example 213-3 23 Example 213-434 Example 213-5 23 Example 213-6 34 Comp. Exam. 214 165 Example 214-130 Example 214-2 44 Example 214-3 35 Example 214-4 31 Example 214-5 23Example 214-6 34 Comp. Exam. 215 115 Example 215-1 45 Example 215-2 42Example 215-3 34 Example 215-4 21 Example 215-5 46 Example 215-6 41Comp. Exam. 216 135 Example 216-1 37 Example 216-2 34 Example 216-3 37Example 216-4 37 Example 216-5 23 Example 216-6 34 Comp. Exam. 217 123Example 217-1 21 Example 217-2 44 Example 217-3 79 Example 217-4 37Example 217-5 56 Example 217-6 23 Comp. Exam. 218 145 Example 218-1 37Example 218-2 23 Example 218-3 34 Example 218-4 37 Example 218-5 23Example 218-6 34 Comp. Exam. 219 153 Example 219-1 31 Example 219-2 44Example 219-3 65 Example 219-4 37 Example 219-5 56 Example 219-6 23Comp. Exam. 220 211 Example 220-1 45 Example 220-2 42 Example 220-3 44Example 220-4 33 Example 220-5 37 Example 220-6 56 Comp. Exam. 221 142Example 221-1 40 Example 221-2 42 Example 221-3 44 Example 221-4 33Example 221-5 37 Example 221-6 56 Comp. Exam. 222 154 Example 222-1 37Example 222-2 33 Example 222-3 23 Example 222-4 43 Example 222-5 23Example 222-6 34 Comp. Exam. 223 224 Example 223-1 31 Example 223-2 44Example 223-3 65 Example 223-4 37 Example 223-5 56 Example 223-6 23Comp. Exam. 224 104 Example 224-1 45 Example 224-2 42 Example 224-3 55Example 224-4 33 Example 224-5 37 Example 224-6 56 Comp. Exam. 225 180Example 225-1 40 Example 225-2 44 Example 225-3 36 Example 225-4 31Example 225-5 37 Example 225-6 41 Comp. Exam. 226 160 Example 226-1 30Example 226-2 54 Example 226-3 35 Example 226-4 37 Example 226-5 23Example 226-6 34 Comp. Exam. 227 114 Example 227-1 45 Example 227-2 42Example 227-3 34 Example 227-4 21 Example 227-5 47 Example 227-6 33Comp. Exam . 228 135 Example 228-1 37 Example 228-2 23 Example 228-3 34Example 228-4 37 Example 228-5 23 Example 228-6 34 Comp. Exam. 229 123Example 229-1 31 Example 229-2 44 Example 229-3 33 Example 229-4 37Example 229-5 56 Example 229-6 23 Comp. Exam. 230 174 Example 230-1 45Example 230-2 42 Example 230-3 44 Example 230-4 33 Example 230-5 37Example 230-6 56 Comp. Exam. 231 166 Example 231-1 37 Example 231-2 55Example 231-3 23 Example 231-4 34 Example 231-5 23 Example 231-6 34

TABLE 12 Sample IC₅₀(ppm) Comp. Exam. 232 115 Example 232-1 45 Example232-2 42 Example 232-3 34 Example 232-4 21 Example 232-5 46 Example232-6 41 Comp. Exam. 233 123 Example 233-1 21 Example 233-2 44 Example233-3 69 Example 233-4 37 Example 233-5 56 Example 233-6 47 Comp. Exam.234 160 Example 234-1 22 Example 234-2 88 Example 234-3 35 Example 234-464 Example 234-5 55 Example 234-6 38 Comp. Exam. 235 135 Example 235-137 Example 235-2 23 Example 235-3 34 Example 235-4 37 Example 235-5 23Example 235-6 34 Comp. Exam. 236 332 Example 236-1 31 Example 236-2 44Example 236-3 42 Example 236-4 47 Example 236-5 56 Example 236-6 64Comp. Exam. 237 178 Example 237-1 30 Example 237-2 44 Example 237-3 35Example 237-4 43 Example 237-5 23 Example 237-6 34 Comp. Exam. 238 165Example 238-1 65 Example 238-2 42 Example 238-3 43 Example 238-4 21Example 238-5 46 Example 238-6 41

As can be seen in Tables 1 to 12 above, the extracts of processedmedicinal plants according to Examples of the present invention showed asignificant inhibition of DPPH oxidation compared to the extracts ofunprocessed medicinal plants of Comparative Examples, suggesting thatthe extracts of Examples of the preset invention showed significantlyexcellent antioxidant activities. Also, the extracts of Examples mostlyshowed excellent antioxidant activity compared to the syntheticantioxidant Trolox.

1. A method of preparing a medicinal plant extract using Chinese herbalmedicine processing, comprising the steps of: (a) processing ofmedicinal plants by boiling or steaming, roasting, baking or heatingthem; and (b) obtaining extracts of the medicinal plants processed inthe step (a) using water or an organic solvent.
 2. The method of claim1, wherein the medicinal plants in the step (a) are at least oneselected from the group consisting of Terminalia chebula Retz flesh,Pueraria root, Angelica koreana, Chrysanthemum indicum, Rehmanniaeradix, Rhus verniciflua Stokes, licorice, dried ginger, Pharbitidissemen, Cassiae semen, Meliae cortex, Angelica tenuissima, Sophoraflavescens, Caragana chamlagu, Trichosanthes semen, Lycii fructus,Agastache rugosa, Selaginella involvens, Citrus peel, Lonicera japonicaflower, Chrysanthemum zawadskii, Chrysanthemum indicum, Platycodongrandiflorum, Cudrania tricuspidata, Raphani semen, Arisaema amurense,Cervi cornus colla, Phaseolus aureus, antler velvet, Trapa japonicafruit, Brassica rapa, Angelica acutiloba, Citrus grandis osbeck, Circiumjaponicum, Glycine semen germinatum, Datura stramonium, Zizyphus jujuba,Dae-cheong-chow, Rheum undulatum, Persicae semen, Aralia continentalisKitagawa, Cordyceps militaris, Eucommiae cortex, suffruticosa, Cnidiumofficinale, Aster root, Lithospermum erythrorhizon, Paeonia, Adenophoratriphylla, Ailanthus altissima bark, Grifola umbellata, Poria cocos red,Polygonum multiflorum Thunberg, red cabbage, Paeoniae Radix Rubra,Anthriscus sylvestris, Sorbus commixta cortex, Syzygium aromaticum,Gleditsiae fructus, Gleditsiae spina, Lophatherum gracile, Cistanchedeserticola, Phyllostachys nigra sheath, Lyceum chinensis root, Hoveniadulcis bark, Anemarrhena asphodeloides, Kochiae fructus, Poncirustrifoliate fruit, Sanguisorba officinalis, Rehmannia glutinosa, Aconitumpseudolaeve Nakai, Phyllanthus urinaria, Citrus unshiu peel, Plantaginissemen, Xanthium strumarium fruit, Cnidii rhizoma, Gastrodia elata,Asparagus cochinchinensis, Zanthoxyli fructus, Semiaquilegia adoxoides,Opuntia humifusa, Dioscorea nipponica Makino, Saussurea involucrata,Trichosanthes kirilowii root, Artemisia apiaceae Herba, Amomi tsao-kofructus, Aconiti ciliare tuber, Gardeniae fructus, Celosiae semen,Althaea rosea, Aquillaria agallocha, Taek-ran, Alisma canaliculatum,Ponciri fructus, Smilacis chinae radix, Cuscutae semen, Ligusticumrhizome, Tetrapanacis medulla, Morinda offcinalis How, Tiglii semen,Taraxaci Herba, Typhae pollen, Calypso bulbosa, Polygonum multiflorumtuber, Aeschynomene indica, Armeniacae semen, Helianthus annus seed,Cyperus rotundus, Elsholtzia ciliata, Cedrela sinensis fruit, Typhaorientalis pollen, Scrophulariae radix, Geranium nepalense, Corydalisturtschaminovii, Schizonepeta tenuifolia, Sesamum indicum, Trigonellafoenum-graecum, Cucurbita spp, Acanthopanax giraldii, red ginseng,Kombucha, Herba Trifolii pratensis, Carthamus tinctorius, floralenvelop, Scutellaria baicalensis Georgi, Astragalus membranaceus, Coptischinensis Franch, Polygonatum lasianthum radix, Lindera obtusilobabranch, Phellodendron amurense bark, Magnolia obovata, black Pharbitissemen, and Siegesbeckiae Herba.
 3. The method of claim 1, wherein theorganic solvent used in the step (b) is at least one selected from thegroup consisting of ethanol, methanol, butanol, ether, ethyl acetate andchloroform. 4.-8. (canceled)